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Structure paper

TitleCompleting the Structural Family Portrait of the Human Ephb Tyrosine Kinase Domains
Journal, issue, pagesProtein Sci., Vol. 23, Page 627-, Year 2014
Publish dateDec 7, 2012 (structure data deposition date)
AuthorsOverman, R.C. / Debreczeni, J.E. / Truman, C.M. / Mcalister, M.S. / Attwood, T.K.
External linksProtein Sci. / PubMed:24677421
MethodsX-ray diffraction
Resolution2.2 - 2.5 Å
Structure data

PDB-3zew:
Crystal structure of EphB4 in complex with staurosporine
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-3zfm:
Crystal structure of EphB2
Method: X-RAY DIFFRACTION / Resolution: 2.27 Å

PDB-3zfx:
Crystal structure of EphB1
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-3zfy:
Crystal structure of EphB3
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-STU:
STAUROSPORINE / anticancer, antifungal, antibiotic, alkaloid*YM

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / INHIBITOR

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