Entry Database : PDB / ID : 3zfb Structure visualization Downloads & linksTitle Crystal structure of the I75A mutant of human class alpha glutathione transferase in the apo form ComponentsGLUTATHIONE S-TRANSFERASE A1 Details Keywords TRANSFERASE / XENOBIOTIC DETOXIFICATION / THIOREDOXIN / TOPOLOGICALLY CONSERVEDFunction / homology Function and homology informationFunction Domain/homology Component
Isomerases; Intramolecular oxidoreductases; Transposing C=C bonds / glutathione derivative biosynthetic process / steroid delta-isomerase activity / linoleic acid metabolic process / Glutathione conjugation / glutathione peroxidase activity / Azathioprine ADME / Heme degradation / NFE2L2 regulating anti-oxidant/detoxification enzymes / prostaglandin metabolic process ... Isomerases; Intramolecular oxidoreductases; Transposing C=C bonds / glutathione derivative biosynthetic process / steroid delta-isomerase activity / linoleic acid metabolic process / Glutathione conjugation / glutathione peroxidase activity / Azathioprine ADME / Heme degradation / NFE2L2 regulating anti-oxidant/detoxification enzymes / prostaglandin metabolic process / glutathione transferase / glutathione transferase activity / Oxidoreductases; Acting on a peroxide as acceptor; Peroxidases / epithelial cell differentiation / xenobiotic metabolic process / glutathione metabolic process / fatty acid binding / extracellular exosome / cytosol Similarity search - Function Glutathione S-transferase, alpha class / Glutathione S-transferase, C-terminal domain / Glutathione S-transferase, N-terminal domain / Glutathione transferase family / Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 - #10 / Glutathione S-transferase, C-terminal / Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 / Soluble glutathione S-transferase N-terminal domain profile. / Glutathione S-transferase, C-terminal-like / Soluble glutathione S-transferase C-terminal domain profile. ... Glutathione S-transferase, alpha class / Glutathione S-transferase, C-terminal domain / Glutathione S-transferase, N-terminal domain / Glutathione transferase family / Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 - #10 / Glutathione S-transferase, C-terminal / Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 / Soluble glutathione S-transferase N-terminal domain profile. / Glutathione S-transferase, C-terminal-like / Soluble glutathione S-transferase C-terminal domain profile. / Glutathione S-transferase, N-terminal / Glutathione S-transferase, C-terminal domain superfamily / Glutaredoxin / Glutaredoxin / Thioredoxin-like superfamily / Up-down Bundle / 3-Layer(aba) Sandwich / Mainly Alpha / Alpha Beta Similarity search - Domain/homologyBiological species HOMO SAPIENS (human)Method X-RAY DIFFRACTION / MOLECULAR REPLACEMENT / Resolution : 1.86 Å DetailsAuthors Parbhoo, N. / Fanucchi, S. / Achilonu, I.A. / Fernandes, M.A. / Gildenhuys, S. / Dirr, H.W. CitationJournal : To be Published Title : Crystal Structure of the I75A Mutant of Human Class Alpha Glutathione Transferase in the Apo FormAuthors : Parbhoo, N. / Achilonu, I.A. / Fanucchi, S. / Fernandes, M.A. / Gildenhuys, S. / Dirr, H.W. History Deposition Dec 11, 2012 Deposition site : PDBE / Processing site : PDBERevision 1.0 Dec 19, 2012 Provider : repository / Type : Initial releaseRevision 1.1 Apr 4, 2018 Group : Data collection / Category : diffrn_source / Item : _diffrn_source.typeRevision 1.2 Jan 30, 2019 Group : Data collection / Experimental preparationCategory : database_PDB_rev / database_PDB_rev_record ... database_PDB_rev / database_PDB_rev_record / exptl_crystal_grow / struct_biol Item : _exptl_crystal_grow.method / _exptl_crystal_grow.tempRevision 1.3 Dec 20, 2023 Group : Data collection / Database references ... Data collection / Database references / Other / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf
Show all Show less