- PDB-3zdm: Crystal structure of the Sgt2 N domain and the Get5 UBL domain complex -
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Basic information
Entry
Database: PDB / ID: 3zdm
Title
Crystal structure of the Sgt2 N domain and the Get5 UBL domain complex
Components
SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT- CONTAINING PROTEIN 2
UBIQUITIN-LIKE PROTEIN MDY2
Keywords
CHAPERONE/SIGNALING PROTEIN / CHAPERONE-SIGNALING PROTEIN COMPLEX
Function / homology
Function and homology information
cell morphogenesis involved in conjugation with cellular fusion / TRC complex / Insertion of tail-anchored proteins into the endoplasmic reticulum membrane / protein insertion into ER membrane / post-translational protein targeting to endoplasmic reticulum membrane / cytoplasmic stress granule / protein-macromolecule adaptor activity / response to heat / molecular adaptor activity / identical protein binding ...cell morphogenesis involved in conjugation with cellular fusion / TRC complex / Insertion of tail-anchored proteins into the endoplasmic reticulum membrane / protein insertion into ER membrane / post-translational protein targeting to endoplasmic reticulum membrane / cytoplasmic stress granule / protein-macromolecule adaptor activity / response to heat / molecular adaptor activity / identical protein binding / membrane / nucleus / cytosol / cytoplasm Similarity search - Function
Mdy2, Get4 binding domain / Get5, C-terminal domain / Binding domain to Get4 on Get5, Golgi to ER traffic protein / Ubiquitin-like protein MDY2, C-terminal domain / SGTA, homodimerisation domain / Homodimerisation domain of SGTA / : / Immunoglobulin FC, subunit C / Tetratricopeptide repeat / TPR repeat region circular profile. ...Mdy2, Get4 binding domain / Get5, C-terminal domain / Binding domain to Get4 on Get5, Golgi to ER traffic protein / Ubiquitin-like protein MDY2, C-terminal domain / SGTA, homodimerisation domain / Homodimerisation domain of SGTA / : / Immunoglobulin FC, subunit C / Tetratricopeptide repeat / TPR repeat region circular profile. / TPR repeat profile. / Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 / Tetratricopeptide repeats / Tetratricopeptide repeat / Single alpha-helices involved in coiled-coils or other helix-helix interfaces / Ubiquitin-like (UB roll) / Ubiquitin family / Ubiquitin homologues / Tetratricopeptide-like helical domain superfamily / Ubiquitin domain profile. / Ubiquitin-like domain / Ubiquitin-like domain superfamily / Roll / Up-down Bundle / Mainly Alpha / Alpha Beta Similarity search - Domain/homology
Small glutamine-rich tetratricopeptide repeat-containing protein 2 / Ubiquitin-like protein MDY2 Similarity search - Component
Biological species
SACCHAROMYCES CEREVISIAE (brewer's yeast)
Method
X-RAY DIFFRACTION / SYNCHROTRON / MAD / Resolution: 1.803 Å
A: SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT- CONTAINING PROTEIN 2 B: SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT- CONTAINING PROTEIN 2 C: UBIQUITIN-LIKE PROTEIN MDY2 D: SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT- CONTAINING PROTEIN 2 E: SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT- CONTAINING PROTEIN 2 F: UBIQUITIN-LIKE PROTEIN MDY2