Entry Database : PDB / ID : 3wmg Structure visualization Downloads & linksTitle Crystal structure of an inward-facing eukaryotic ABC multidrug transporter G277V/A278V/A279V mutant in complex with an cyclic peptide inhibitor, aCAP ComponentsATP-binding cassette, sub-family B, member 1 anti-CmABCB1 peptide DetailsKeywords TRANSPORT PROTEIN/INHIBITOR / Rec fold / Multi drug transporter / Macrocyclic peptide / TRANSPORT PROTEIN-INHIBITOR COMPLEXFunction / homology Function and homology informationFunction Domain/homology Component
ABC-type transporter activity / chloroplast / ATP hydrolysis activity / ATP binding / membrane / metal ion binding Similarity search - Function ABC transporter transmembrane region fold / ABC transporter type 1, transmembrane domain / Type 1 protein exporter / ABC transporter transmembrane region / ABC transporter type 1, transmembrane domain / ABC transporter integral membrane type-1 fused domain profile. / ABC transporter type 1, transmembrane domain superfamily / ABC transporter-like, conserved site / ABC transporters family signature. / ABC transporter ... ABC transporter transmembrane region fold / ABC transporter type 1, transmembrane domain / Type 1 protein exporter / ABC transporter transmembrane region / ABC transporter type 1, transmembrane domain / ABC transporter integral membrane type-1 fused domain profile. / ABC transporter type 1, transmembrane domain superfamily / ABC transporter-like, conserved site / ABC transporters family signature. / ABC transporter / ABC transporter-like, ATP-binding domain / ATP-binding cassette, ABC transporter-type domain profile. / P-loop containing nucleotide triphosphate hydrolases / ATPases associated with a variety of cellular activities / AAA+ ATPase domain / Up-down Bundle / Rossmann fold / P-loop containing nucleoside triphosphate hydrolase / 3-Layer(aba) Sandwich / Mainly Alpha / Alpha Beta Similarity search - Domain/homologyBiological species Cyanidioschyzon merolae (eukaryote)Method X-RAY DIFFRACTION / SYNCHROTRON / FOURIER SYNTHESIS / Resolution : 2.4 Å DetailsAuthors Kodan, A. / Yamaguchi, T. / Nakatsu, T. / Sakiyama, K. / Hipolito, C.J. / Fujioka, A. / Hirokane, R. / Ikeguchi, K. / Watanabe, B. / Hirtake, J. ...Kodan, A. / Yamaguchi, T. / Nakatsu, T. / Sakiyama, K. / Hipolito, C.J. / Fujioka, A. / Hirokane, R. / Ikeguchi, K. / Watanabe, B. / Hirtake, J. / Kimura, Y. / Suga, H. / Ueda, K. / Kato, H. CitationJournal : Proc.Natl.Acad.Sci.USA / Year : 2014Title : Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog.Authors : Kodan, A. / Yamaguchi, T. / Nakatsu, T. / Sakiyama, K. / Hipolito, C.J. / Fujioka, A. / Hirokane, R. / Ikeguchi, K. / Watanabe, B. / Hiratake, J. / Kimura, Y. / Suga, H. / Ueda, K. / Kato, H. History Deposition Nov 18, 2013 Deposition site : PDBJ / Processing site : PDBJRevision 1.0 Apr 30, 2014 Provider : repository / Type : Initial releaseRevision 1.1 May 14, 2014 Group : Non-polymer descriptionRevision 1.2 Nov 22, 2017 Group : Refinement description / Category : software
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