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Open data
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Basic information
Entry | Database: PDB / ID: 3vg7 | ||||||
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Title | Structure of human LFABP at high resolution from S-SAD | ||||||
![]() | Fatty acid-binding protein, liver | ||||||
![]() | LIPID BINDING PROTEIN / LFABP / S-SAD / Copper Kalpha / Palmitic acid | ||||||
Function / homology | ![]() response to vitamin B3 / oleic acid binding / apical cortex / positive regulation of fatty acid beta-oxidation / bile acid binding / intestinal absorption / Heme degradation / long-chain fatty acid transmembrane transporter activity / heterocyclic compound binding / Triglyceride catabolism ...response to vitamin B3 / oleic acid binding / apical cortex / positive regulation of fatty acid beta-oxidation / bile acid binding / intestinal absorption / Heme degradation / long-chain fatty acid transmembrane transporter activity / heterocyclic compound binding / Triglyceride catabolism / antioxidant activity / peroxisomal matrix / fatty acid transport / Regulation of lipid metabolism by PPARalpha / fatty acid binding / negative regulation of cysteine-type endopeptidase activity involved in apoptotic process / PPARA activates gene expression / Cytoprotection by HMOX1 / phospholipid binding / cellular response to hydrogen peroxide / cellular response to hypoxia / chromatin binding / negative regulation of apoptotic process / protein-containing complex / extracellular exosome / nucleoplasm / nucleus / cytosol Similarity search - Function | ||||||
Biological species | ![]() | ||||||
Method | ![]() ![]() | ||||||
![]() | Sharma, A. / Yogavel, M. / Sharma, A. | ||||||
![]() | ![]() Title: Utility of anion and cation combinations for phasing of protein structures. Authors: Sharma, A. / Yogavel, M. / Sharma, A. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 46.3 KB | Display | ![]() |
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PDB format | ![]() | 32 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 785 KB | Display | ![]() |
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Full document | ![]() | 788.7 KB | Display | |
Data in XML | ![]() | 11.4 KB | Display | |
Data in CIF | ![]() | 16.3 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 3b2hC ![]() 3b2iC ![]() 3b2jC ![]() 3b2kC ![]() 3b2lC ![]() 3vg2C ![]() 3vg3C ![]() 3vg4C ![]() 3vg5C ![]() 3vg6C C: citing same article ( |
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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1 |
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Unit cell |
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Components
#1: Protein | Mass: 14599.728 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() | ||
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#2: Chemical | #3: Water | ChemComp-HOH / | |
-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 1.94 Å3/Da / Density % sol: 44.22 % / Description: THE FILE CONTAINS FRIEDEL PAIRS. |
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Crystal grow | Temperature: 293 K / Method: hanging drop / pH: 8 Details: 30% PEG MME 2000, 0.15M KBr, pH 8.0, hanging drop, temperature 293K |
-Data collection
Diffraction | Mean temperature: 100 K |
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Diffraction source | Source: ![]() |
Detector | Type: MAR scanner 345 mm plate / Detector: IMAGE PLATE / Date: Sep 10, 2009 / Details: mirrors |
Radiation | Monochromator: SAGITALLY FOCUSED Si(111) / Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength: 1.5418 Å / Relative weight: 1 |
Reflection | Resolution: 1.43→50 Å / Num. obs: 24038 / % possible obs: 97.3 % / Observed criterion σ(F): 2 / Observed criterion σ(I): 2 / Redundancy: 2.4 % / Rmerge(I) obs: 0.051 / Net I/σ(I): 103.7 |
Reflection shell | Resolution: 1.43→1.48 Å / Redundancy: 23.2 % / Rmerge(I) obs: 0.417 / Mean I/σ(I) obs: 9.8 / Num. unique all: 2020 / % possible all: 84.6 |
-Phasing
Phasing | Method: ![]() |
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Processing
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Refinement | Method to determine structure: AB INITIO / Resolution: 1.44→6.5 Å / Num. parameters: 10853 / Num. restraintsaints: 13584 / Occupancy max: 1.15 / σ(F): 0 / Stereochemistry target values: ENGH & HUBER / Details: THE FILE CONTAINS FRIEDEL PAIRS.
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Displacement parameters | Biso max: 156.55 Å2 / Biso mean: 25.6919 Å2 / Biso min: 13.31 Å2 | ||||||||||||||||||||||||||||||||
Refinement step | Cycle: LAST / Resolution: 1.44→6.5 Å
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