登録情報 データベース : PDB / ID : 3u0z 構造の表示 ダウンロードとリンクタイトル Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels 要素Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 詳細 キーワード TRANSPORT PROTEIN / helix / beta sheet / cNMP binding機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
HCN channels / regulation of membrane hyperpolarization / HCN channel complex / retinal cone cell development / : / positive regulation of cation channel activity / negative regulation of action potential / regulation of membrane depolarization / intracellularly cAMP-activated cation channel activity / apical protein localization ... HCN channels / regulation of membrane hyperpolarization / HCN channel complex / retinal cone cell development / : / positive regulation of cation channel activity / negative regulation of action potential / regulation of membrane depolarization / intracellularly cAMP-activated cation channel activity / apical protein localization / apical dendrite / voltage-gated monoatomic cation channel activity / voltage-gated sodium channel activity / voltage-gated potassium channel activity / plasma membrane => GO:0005886 / phosphatidylinositol-3,4,5-trisphosphate binding / sodium ion transmembrane transport / axon terminus / cAMP binding / cellular response to cAMP / potassium ion transmembrane transport / somatodendritic compartment / dendrite membrane / phosphatidylinositol-4,5-bisphosphate binding / dendritic shaft / regulation of membrane potential / response to calcium ion / basolateral plasma membrane / protein homotetramerization / axon / neuronal cell body / synapse / dendrite / protein-containing complex binding / cell surface / identical protein binding / plasma membrane / cytoplasm 類似検索 - 分子機能 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 / Helix hairpin bin / Ion transport N-terminal / Ion transport protein N-terminal / Potassium channel, voltage-dependent, EAG/ELK/ERG / Cyclic nucleotide-binding domain signature 1. / Cyclic nucleotide-binding, conserved site / Cyclic nucleotide-monophosphate binding domain / Cyclic nucleotide-binding domain / cAMP/cGMP binding motif profile. ... Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 / Helix hairpin bin / Ion transport N-terminal / Ion transport protein N-terminal / Potassium channel, voltage-dependent, EAG/ELK/ERG / Cyclic nucleotide-binding domain signature 1. / Cyclic nucleotide-binding, conserved site / Cyclic nucleotide-monophosphate binding domain / Cyclic nucleotide-binding domain / cAMP/cGMP binding motif profile. / Cyclic nucleotide-binding domain / Cyclic nucleotide-binding domain superfamily / Jelly Rolls / Voltage-dependent channel domain superfamily / RmlC-like jelly roll fold / Ion transport domain / Ion transport protein / Helix Hairpins / Jelly Rolls / Sandwich / Orthogonal Bundle / Mainly Beta / Mainly Alpha 類似検索 - ドメイン・相同性 ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE / Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 類似検索 - 構成要素生物種 Mus musculus (ハツカネズミ)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.9 Å 詳細データ登録者 Lolicato, M. / Nardini, M. / Gazzarrini, S. / Moller, S. / Bertinetti, D. / Herberg, F.W. / Bolognesi, M. / Martin, H. / Fasolini, M. / Bertrand, J.A. ...Lolicato, M. / Nardini, M. / Gazzarrini, S. / Moller, S. / Bertinetti, D. / Herberg, F.W. / Bolognesi, M. / Martin, H. / Fasolini, M. / Bertrand, J.A. / Arrigoni, C. / Thiel, G. / Moroni, A. 引用ジャーナル : J.Biol.Chem. / 年 : 2011タイトル : Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.著者 : Lolicato, M. / Nardini, M. / Gazzarrini, S. / Moller, S. / Bertinetti, D. / Herberg, F.W. / Bolognesi, M. / Martin, H. / Fasolini, M. / Bertrand, J.A. / Arrigoni, C. / Thiel, G. / Moroni, A. 履歴 登録 2011年9月29日 登録サイト : RCSB / 処理サイト : PDBJ改定 1.0 2011年10月26日 Provider : repository / タイプ : Initial release改定 1.1 2013年7月10日 Group : Database references改定 1.2 2023年11月1日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ncs_dom_lim / struct_ref_seq_dif / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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