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Yorodumi- PDB-3ptb: THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TR... -
+Open data
-Basic information
Entry | Database: PDB / ID: 3ptb | |||||||||
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Title | THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS | |||||||||
Components | BETA-TRYPSIN | |||||||||
Keywords | HYDROLASE (SERINE PROTEINASE) | |||||||||
Function / homology | Function and homology information trypsin / serpin family protein binding / serine protease inhibitor complex / digestion / endopeptidase activity / serine-type endopeptidase activity / proteolysis / extracellular space / metal ion binding Similarity search - Function | |||||||||
Biological species | Bos taurus (cattle) | |||||||||
Method | X-RAY DIFFRACTION / Resolution: 1.7 Å | |||||||||
Authors | Bode, W. / Schwager, P. / Walter, J. | |||||||||
Citation | Journal: Acta Crystallogr.,Sect.B / Year: 1983 Title: The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors Authors: Marquart, M. / Walter, J. / Deisenhofer, J. / Bode, W. / Huber, R. #1: Journal: Miami Winter Symp. / Year: 1976 Title: Structural Studies on the Pancreatic Trypsin Inhibitor-Trypsin Complex and its Free Components. Structure and Function Relationships in Serine Protease Inhibition and Catalysis Authors: Bode, W. / Schwager, P. / Huber, R. #2: Journal: J.Mol.Biol. / Year: 1975 Title: The Refined Crystal Structure of Bovine Beta-Trypsin at 1.8 Angstroms Resolution. I. Crystallization, Data Collection and Application of Patterson Search Techniques Authors: Fehlhammer, H. / Bode, W. #3: Journal: J.Mol.Biol. / Year: 1975 Title: The Refined Crystal Structure of Bovine Beta-Trypsin at 1.8 Angstroms Resolution. II. Crystallographic Refinement, Calcium Binding Site, Benzamidine Binding Site and Active Site at Ph 7.0 Authors: Bode, W. / Schwager, P. #4: Journal: FEBS Lett. / Year: 1975 Title: The Single Calcium-Binding Site of Crystalline Bovine Beta-Trypsin Authors: Bode, W. / Schwager, P. | |||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 3ptb.cif.gz | 52.6 KB | Display | PDBx/mmCIF format |
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PDB format | pdb3ptb.ent.gz | 37.7 KB | Display | PDB format |
PDBx/mmJSON format | 3ptb.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/pt/3ptb ftp://data.pdbj.org/pub/pdb/validation_reports/pt/3ptb | HTTPS FTP |
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-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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Unit cell |
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Atom site foot note | 1: SEE REMARK 4. |
-Components
#1: Protein | Mass: 23324.287 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Bos taurus (cattle) / References: UniProt: P00760, trypsin |
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#2: Chemical | ChemComp-CA / |
#3: Chemical | ChemComp-BEN / |
#4: Water | ChemComp-HOH / |
-Experimental details
-Experiment
Experiment | Method: X-RAY DIFFRACTION |
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-Sample preparation
Crystal | Density Matthews: 2.33 Å3/Da / Density % sol: 47.16 % |
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Crystal grow | *PLUS Method: unknown |
-Processing
Refinement | Resolution: 1.7→7 Å / Rfactor Rwork: 0.182 | ||||||||||||
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Refinement step | Cycle: LAST / Resolution: 1.7→7 Å
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