登録情報 データベース : PDB / ID : 3pm0 構造の表示 ダウンロードとリンクタイトル Structural Characterization of the Complex between Alpha-Naphthoflavone and Human Cytochrome P450 1B1 (CYP1B1) 要素Cytochrome P450 1B1 詳細 キーワード OXIDOREDUCTASE / CYP1B1 / P450 1B1 / P450 / MONOOXYGENASE / ALPHA-NAPHTHOFLAVONE / HEME / 17BETA-ESTRADIOL機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
trabecular meshwork development / cellular response to cortisol stimulus / response to indole-3-methanol / Defective CYP1B1 causes Glaucoma / endothelial cell-cell adhesion / benzene-containing compound metabolic process / membrane lipid catabolic process / hydroperoxy icosatetraenoate dehydratase / hydroperoxy icosatetraenoate dehydratase activity / ganglion development ... trabecular meshwork development / cellular response to cortisol stimulus / response to indole-3-methanol / Defective CYP1B1 causes Glaucoma / endothelial cell-cell adhesion / benzene-containing compound metabolic process / membrane lipid catabolic process / hydroperoxy icosatetraenoate dehydratase / hydroperoxy icosatetraenoate dehydratase activity / ganglion development / retinal blood vessel morphogenesis / Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) / response to follicle-stimulating hormone / omega-hydroxylase P450 pathway / response to 3-methylcholanthrene / toxin metabolic process / epoxygenase P450 pathway / blood vessel endothelial cell migration / arachidonic acid metabolic process / cellular response to toxic substance / DNA modification / estrogen 16-alpha-hydroxylase activity / retinal metabolic process / cellular response to progesterone stimulus / cellular response to luteinizing hormone stimulus / Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) / sterol metabolic process / negative regulation of cell adhesion mediated by integrin / response to arsenic-containing substance / oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen / collagen fibril organization / blood vessel morphogenesis / regulation of reactive oxygen species metabolic process / estrogen metabolic process / retinol metabolic process / unspecific monooxygenase / aromatase activity / intrinsic apoptotic signaling pathway in response to oxidative stress / adrenal gland development / positive regulation of DNA biosynthetic process / negative regulation of NF-kappaB transcription factor activity / response to dexamethasone / positive regulation of smooth muscle cell migration / steroid metabolic process / cellular response to organic cyclic compound / estrous cycle / positive regulation of vascular endothelial growth factor production / endothelial cell migration / Endogenous sterols / cellular response to cAMP / nitric oxide biosynthetic process / monooxygenase activity / xenobiotic metabolic process / negative regulation of cell migration / response to nutrient / positive regulation of translation / positive regulation of receptor signaling pathway via JAK-STAT / cellular response to hydrogen peroxide / positive regulation of angiogenesis / male gonad development / positive regulation of reactive oxygen species metabolic process / response to estradiol / cellular response to tumor necrosis factor / angiogenesis / cell adhesion / iron ion binding / positive regulation of apoptotic process / negative regulation of cell population proliferation / intracellular membrane-bounded organelle / heme binding / endoplasmic reticulum membrane / mitochondrion 類似検索 - 分子機能 Cytochrome P450, E-class, group I / Cytochrome p450 / Cytochrome P450 / Cytochrome P450, conserved site / Cytochrome P450 cysteine heme-iron ligand signature. / Cytochrome P450 / Cytochrome P450 superfamily / Cytochrome P450 / Orthogonal Bundle / Mainly Alpha 類似検索 - ドメイン・相同性 2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE / PROTOPORPHYRIN IX CONTAINING FE / Cytochrome P450 1B1 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.7 Å 詳細データ登録者 Wang, A. / Stout, C.D. / Johnson, E.F. 引用ジャーナル : J.Biol.Chem. / 年 : 2011タイトル : Structural Characterization of the Complex between {alpha}-Naphthoflavone and Human Cytochrome P450 1B1.著者 : Wang, A. / Savas, U. / Stout, C.D. / Johnson, E.F. 履歴 登録 2010年11月15日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2010年12月8日 Provider : repository / タイプ : Initial release改定 1.1 2011年7月13日 Group : Version format compliance改定 1.2 2024年2月21日 Group : Data collection / Database references / Derived calculationsカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / struct_ref_seq_dif / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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