登録情報 | データベース: PDB / ID: 3kio |
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タイトル | mouse RNase H2 complex |
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要素 | - Ribonuclease H2 subunit A
- Ribonuclease H2 subunit B
- Ribonuclease H2 subunit C
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キーワード | HYDROLASE / ribonuclease / Aicardi-Goutieres syndrome / RNase H2 / protein complex / autoimmune disease / Endonuclease / Metal-binding / Nuclease / Nucleus / Phosphoprotein / Acetylation |
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機能・相同性 | 機能・相同性情報
ribonucleotide metabolic process / ribonuclease H2 complex / regulation of DNA damage checkpoint / RNA catabolic process / ribonuclease H / mismatch repair / regulation of G2/M transition of mitotic cell cycle / positive regulation of fibroblast proliferation / RNA-DNA hybrid ribonuclease activity / fibroblast proliferation ...ribonucleotide metabolic process / ribonuclease H2 complex / regulation of DNA damage checkpoint / RNA catabolic process / ribonuclease H / mismatch repair / regulation of G2/M transition of mitotic cell cycle / positive regulation of fibroblast proliferation / RNA-DNA hybrid ribonuclease activity / fibroblast proliferation / gene expression / in utero embryonic development / negative regulation of gene expression / RNA binding / nucleoplasm / metal ion binding / nucleus / cytosol類似検索 - 分子機能 Lipocalin - #680 / Ribonuclease H2, subunit C / : / Ribonuclease H2 non-catalytic subunit (Ylr154p-like) / Ribonuclease H2 subunit B, wHTH domain / Ribonuclease H2 subunit B / Rnh202, triple barrel domain / Ydr279p protein family (RNase H2 complex component) wHTH domain / Ydr279p protein triple barrel domain / Ribonuclease hii. Domain 2 ...Lipocalin - #680 / Ribonuclease H2, subunit C / : / Ribonuclease H2 non-catalytic subunit (Ylr154p-like) / Ribonuclease H2 subunit B, wHTH domain / Ribonuclease H2 subunit B / Rnh202, triple barrel domain / Ydr279p protein family (RNase H2 complex component) wHTH domain / Ydr279p protein triple barrel domain / Ribonuclease hii. Domain 2 / Ribonuclease HII, helix-loop-helix cap domain superfamily / Ribonuclease H2, subunit A / Ribonuclease HII/HIII / Ribonuclease HII/HIII domain / Ribonuclease HII / Ribonuclease (RNase) H type-2 domain profile. / Ribonuclease H-like superfamily/Ribonuclease H / Lipocalin / Nucleotidyltransferase; domain 5 / Arc Repressor Mutant, subunit A / Ribonuclease H superfamily / Ribonuclease H-like superfamily / Beta Barrel / 2-Layer Sandwich / Orthogonal Bundle / Mainly Beta / Mainly Alpha / Alpha Beta類似検索 - ドメイン・相同性 Ribonuclease H2 subunit B / Ribonuclease H2 subunit C / Ribonuclease H2 subunit A類似検索 - 構成要素 |
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生物種 |  Mus musculus (ハツカネズミ) |
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手法 | X線回折 / シンクロトロン / 多波長異常分散 / 解像度: 2.9 Å |
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データ登録者 | Shaban, N. / Harvey, S. / Perrino, F.W. / Hollis, T. |
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引用 | ジャーナル: J.Biol.Chem. / 年: 2010 タイトル: The structure of the mammalian RNase H2 complex provides insight into RNA:DNA hybrid processing to prevent immune dysfunction. 著者: Shaban, N.M. / Harvey, S. / Perrino, F.W. / Hollis, T. |
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履歴 | 登録 | 2009年11月2日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2009年11月17日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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改定 1.2 | 2024年11月20日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Structure summary カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_entry_details / pdbx_modification_feature / struct_conn / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_leaving_atom_flag / _struct_ref_seq_dif.details |
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