登録情報 | データベース: PDB / ID: 3i9a |
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タイトル | Crystal structure of human transthyretin variant A25T - #1 |
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要素 | Transthyretin |
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キーワード | HORMONE / human transthyretin / A25T / amyloidosis / Amyloid / Disease mutation / Gamma-carboxyglutamic acid / Glycoprotein / Neuropathy / Retinol-binding / Secreted / Thyroid hormone / Transport / Vitamin A |
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機能・相同性 | 機能・相同性情報
Retinoid cycle disease events / The canonical retinoid cycle in rods (twilight vision) / thyroid hormone binding / purine nucleobase metabolic process / Non-integrin membrane-ECM interactions / Retinoid metabolism and transport / hormone activity / azurophil granule lumen / Amyloid fiber formation / Neutrophil degranulation ...Retinoid cycle disease events / The canonical retinoid cycle in rods (twilight vision) / thyroid hormone binding / purine nucleobase metabolic process / Non-integrin membrane-ECM interactions / Retinoid metabolism and transport / hormone activity / azurophil granule lumen / Amyloid fiber formation / Neutrophil degranulation / extracellular space / extracellular exosome / extracellular region / identical protein binding類似検索 - 分子機能 Transthyretin/hydroxyisourate hydrolase domain / Transthyretin, conserved site / Transthyretin signature 2. / Transthyretin, thyroxine binding site / Transthyretin signature 1. / Transthyretin / Transthyretin/hydroxyisourate hydrolase / Transthyretin/hydroxyisourate hydrolase domain / Transthyretin/hydroxyisourate hydrolase domain superfamily / HIUase/Transthyretin family ...Transthyretin/hydroxyisourate hydrolase domain / Transthyretin, conserved site / Transthyretin signature 2. / Transthyretin, thyroxine binding site / Transthyretin signature 1. / Transthyretin / Transthyretin/hydroxyisourate hydrolase / Transthyretin/hydroxyisourate hydrolase domain / Transthyretin/hydroxyisourate hydrolase domain superfamily / HIUase/Transthyretin family / Immunoglobulin-like / Sandwich / Mainly Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.65 Å |
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データ登録者 | Palmieri, L.C. / Freire, J.B.B. / Palhano, F.L. / Azevedo, E.P.C. / Foguel, D. / Lima, L.M.T.R. |
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引用 | ジャーナル: To be Published タイトル: Crystal structure of human transthyretin variant A25T - #1 著者: Palmieri, L.C. / Freire, J.B.B. / Palhano, F.L. / Azevedo, E.P.C. / Foguel, D. / Lima, L.M.T.R. |
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履歴 | 登録 | 2009年7月10日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2010年8月25日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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改定 1.2 | 2019年9月25日 | Group: Advisory / Data collection / Derived calculations カテゴリ: pdbx_distant_solvent_atoms / pdbx_struct_assembly ...pdbx_distant_solvent_atoms / pdbx_struct_assembly / pdbx_struct_assembly_gen / pdbx_struct_assembly_prop / pdbx_struct_oper_list Item: _pdbx_struct_assembly_prop.biol_id / _pdbx_struct_assembly_prop.value |
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改定 1.3 | 2021年10月13日 | Group: Database references / Derived calculations / カテゴリ: database_2 / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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改定 1.4 | 2023年9月6日 | Group: Data collection / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model |
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