登録情報 データベース : PDB / ID : 3c6m 構造の表示 ダウンロードとリンクタイトル Crystal structure of human spermine synthase in complex with spermine and 5-methylthioadenosine 要素Spermine synthase 詳細 キーワード TRANSFERASE / SPERMIDINE AMINOPROPYLTRANSFERASE / SPMSY / STRUCTURAL GENOMICS / STRUCTURAL GENOMICS CONSORTIUM / SGC / Phosphoprotein機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
spermine synthase / spermine synthase activity / spermine biosynthetic process / Metabolism of polyamines / polyamine metabolic process / methionine metabolic process / extracellular exosome / cytosol 類似検索 - 分子機能 Spermine synthase, animal / Spermine synthase, N-terminal / S-adenosylmethionine decarboxylase N -terminal / Sirohaem synthase, central domain / Spermidine synthase, tetramerisation domain / Polyamine biosynthesis domain, conserved site / Polyamine biosynthesis (PABS) domain signature. / Polyamine biosynthesis domain / Spermidine synthase, tetramerisation domain / Spermidine synthase, tetramerisation domain superfamily ... Spermine synthase, animal / Spermine synthase, N-terminal / S-adenosylmethionine decarboxylase N -terminal / Sirohaem synthase, central domain / Spermidine synthase, tetramerisation domain / Polyamine biosynthesis domain, conserved site / Polyamine biosynthesis (PABS) domain signature. / Polyamine biosynthesis domain / Spermidine synthase, tetramerisation domain / Spermidine synthase, tetramerisation domain superfamily / Spermidine synthase tetramerisation domain / Polyamine biosynthesis (PABS) domain profile. / Spermine/spermidine synthase domain / Spermidine Synthase; Chain: A, domain 2 / Double Stranded RNA Binding Domain / Vaccinia Virus protein VP39 / Roll / S-adenosyl-L-methionine-dependent methyltransferase superfamily / Rossmann fold / 2-Layer Sandwich / 3-Layer(aba) Sandwich / Mainly Beta / Alpha Beta 類似検索 - ドメイン・相同性 5'-DEOXY-5'-METHYLTHIOADENOSINE / SPERMINE / Spermine synthase 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / 分子置換 / 解像度 : 2.45 Å 詳細データ登録者 Min, J. / Wu, H. / Zeng, H. / Loppnau, P. / Weigelt, J. / Sundstrom, M. / Arrowsmith, C.H. / Edwards, A.M. / Bochkarev, A. / Pegg, A.E. ...Min, J. / Wu, H. / Zeng, H. / Loppnau, P. / Weigelt, J. / Sundstrom, M. / Arrowsmith, C.H. / Edwards, A.M. / Bochkarev, A. / Pegg, A.E. / Plotnikov, A.N. / Structural Genomics Consortium (SGC) 引用ジャーナル : J.Biol.Chem. / 年 : 2008タイトル : Crystal structure of human spermine synthase: implications of substrate binding and catalytic mechanism.著者 : Wu, H. / Min, J. / Zeng, H. / McCloskey, D.E. / Ikeguchi, Y. / Loppnau, P. / Michael, A.J. / Pegg, A.E. / Plotnikov, A.N. 履歴 登録 2008年2月4日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2008年2月19日 Provider : repository / タイプ : Initial release改定 1.1 2011年7月13日 Group : Version format compliance改定 1.2 2023年8月30日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ref_seq_dif / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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