登録情報 データベース : PDB / ID : 2xv5 構造の表示 ダウンロードとリンクタイトル Human lamin A coil 2B fragment 要素LAMIN-A/C 詳細 キーワード STRUCTURAL PROTEIN / INTERMEDIATE FILAMENTS / NUCLEAR MEMBRANE / LEFT-HANDED COILED COIL / RIGHT-HANDED COILED COIL機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
structural constituent of nuclear lamina / negative regulation of mesenchymal cell proliferation / establishment or maintenance of microtubule cytoskeleton polarity / ventricular cardiac muscle cell development / Breakdown of the nuclear lamina / Depolymerization of the Nuclear Lamina / DNA double-strand break attachment to nuclear envelope / Nuclear Envelope Breakdown / nuclear envelope organization / nuclear pore localization ... structural constituent of nuclear lamina / negative regulation of mesenchymal cell proliferation / establishment or maintenance of microtubule cytoskeleton polarity / ventricular cardiac muscle cell development / Breakdown of the nuclear lamina / Depolymerization of the Nuclear Lamina / DNA double-strand break attachment to nuclear envelope / Nuclear Envelope Breakdown / nuclear envelope organization / nuclear pore localization / lamin filament / protein localization to nuclear envelope / nuclear lamina / XBP1(S) activates chaperone genes / Initiation of Nuclear Envelope (NE) Reformation / regulation of protein localization to nucleus / nuclear migration / regulation of telomere maintenance / negative regulation of cardiac muscle hypertrophy in response to stress / muscle organ development / intermediate filament / Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models / negative regulation of release of cytochrome c from mitochondria / protein localization to nucleus / heterochromatin formation / regulation of cell migration / Meiotic synapsis / negative regulation of extrinsic apoptotic signaling pathway / regulation of protein stability / protein localization / structural constituent of cytoskeleton / nuclear matrix / protein import into nucleus / cellular senescence / Signaling by BRAF and RAF1 fusions / nuclear envelope / site of double-strand break / cellular response to hypoxia / nuclear membrane / nuclear speck / negative regulation of cell population proliferation / positive regulation of gene expression / structural molecule activity / perinuclear region of cytoplasm / nucleoplasm / identical protein binding / nucleus / cytosol 類似検索 - 分子機能 Lamin tail domain superfamily / Lamin tail domain / Lamin Tail Domain / Lamin-tail (LTD) domain profile. / Intermediate filament protein, conserved site / Intermediate filament protein / Intermediate filament (IF) rod domain signature. / Intermediate filament, rod domain / Intermediate filament (IF) rod domain profile. / Intermediate filament protein ... Lamin tail domain superfamily / Lamin tail domain / Lamin Tail Domain / Lamin-tail (LTD) domain profile. / Intermediate filament protein, conserved site / Intermediate filament protein / Intermediate filament (IF) rod domain signature. / Intermediate filament, rod domain / Intermediate filament (IF) rod domain profile. / Intermediate filament protein / Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #170 / Single alpha-helices involved in coiled-coils or other helix-helix interfaces / Up-down Bundle / Mainly Alpha 類似検索 - ドメイン・相同性生物種 HOMO SAPIENS (ヒト)手法 X線回折 / シンクロトロン / 単波長異常分散 / 解像度 : 2.4 Å 詳細データ登録者 Kapinos, L.E. / Burkhard, P. / Aebi, U. / Herrmann, H. / Strelkov, S.V. 引用ジャーナル : J.Mol.Biol. / 年 : 2011タイトル : Simultaneous Formation of Right- and Left-Handed Anti-Parallel Coiled-Coil Interfaces by a Coil2 Fragment of Human Lamin A.著者 : Kapinos, L.E. / Burkhard, P. / Herrmann, H. / Aebi, U. / Strelkov, S.V. 履歴 登録 2010年10月22日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2011年3月9日 Provider : repository / タイプ : Initial release改定 1.1 2011年5月8日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance改定 1.3 2019年3月6日 Group : Data collection / Derived calculations ... Data collection / Derived calculations / Experimental preparation / Other カテゴリ : exptl_crystal_grow / pdbx_database_proc ... exptl_crystal_grow / pdbx_database_proc / pdbx_database_status / struct_conn Item : _exptl_crystal_grow.temp / _pdbx_database_status.recvd_author_approval / _struct_conn.pdbx_leaving_atom_flag
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