Entry Database : PDB / ID : 2x1e Structure visualization Downloads & linksTitle The crystal structure of mature acyl coenzyme A:isopenicillin N acyltransferase from Penicillium chrysogenum in complex 6- aminopenicillanic acid ComponentsACYL-COENZYME Details Keywords TRANSFERASE / ZYMOGEN / NTN-HYDROLASE / PENICILLIN BIOSYNTHESIS / ACYLTRANSFERASE / ANTIBIOTIC BIOSYNTHESISFunction / homology Function and homology informationFunction Domain/homology Component
isopenicillin-N N-acyltransferase / isopenicillin-N N-acyltransferase activity / acyl coenzyme A: isopenicillin N acyltransferase activity / penicillin biosynthetic process / peroxisomal matrix Similarity search - Function Arc Repressor Mutant, subunit A - #2120 / : / : / Peptidase C45 / Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase / Penicillin V Acylase; Chain A / Penicillin V Acylase; Chain A / 4-Layer Sandwich / Arc Repressor Mutant, subunit A / Orthogonal Bundle ... Arc Repressor Mutant, subunit A - #2120 / : / : / Peptidase C45 / Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase / Penicillin V Acylase; Chain A / Penicillin V Acylase; Chain A / 4-Layer Sandwich / Arc Repressor Mutant, subunit A / Orthogonal Bundle / Mainly Alpha / Alpha Beta Similarity search - Domain/homologyBiological species PENICILLIUM CHRYSOGENUM (fungus)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2 Å DetailsAuthors Bokhove, M. / Yoshida, H. / Hensgens, C.M.H. / van der Laan, J.M. / Sutherland, J.D. / Dijkstra, B.W. CitationJournal : Structure / Year : 2010Title : Structures of an Isopenicillin N Converting Ntn-Hydrolase Reveal Different Catalytic Roles for the Active Site Residues of Precursor and Mature Enzyme.Authors : Bokhove, M. / Yoshida, H. / Hensgens, C.M.H. / Van Der Laan, J.M. / Sutherland, J.D. / Dijkstra, B.W. History Deposition Dec 23, 2009 Deposition site : PDBE / Processing site : PDBERevision 1.0 Mar 9, 2010 Provider : repository / Type : Initial releaseRevision 1.1 Dec 28, 2011 Group : Database references / Derived calculations ... Database references / Derived calculations / Non-polymer description / Refinement description / Version format compliance Revision 1.2 Nov 5, 2014 Group : Atomic model / Derived calculations ... Atomic model / Derived calculations / Non-polymer description / Other / Structure summary Revision 1.3 Jul 24, 2019 Group : Data collection / Derived calculations / Category : diffrn_source / struct_connItem : _diffrn_source.pdbx_synchrotron_site / _struct_conn.pdbx_leaving_atom_flagRevision 1.4 Dec 20, 2023 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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