Entry Database : PDB / ID : 2vwr Structure visualization Downloads & linksTitle Crystal structure of the second pdz domain of numb-binding protein 2 ComponentsLIGAND OF NUMB PROTEIN X 2 Details Keywords PROTEIN BINDING / PROTEIN-BINDING / METAL-BINDING / LIGAND OF NUMB PROTEIN / ZINC / LNX2_HUMAN / ZINC-FINGER / POLYMORPHISM / RING FINGER PROTEIN 1 / CASP8 PROTEIN-BINDINGFunction / homology Function and homology informationFunction Domain/homology Component
neural precursor cell proliferation / PDZ domain binding / neuron differentiation / ubiquitin-protein transferase activity / identical protein binding / metal ion binding / plasma membrane Similarity search - Function Zinc finger, C3HC4 type (RING finger) / PDZ domain / Pdz3 Domain / Zinc finger, RING-type, conserved site / Zinc finger RING-type signature. / Ring finger / PDZ domain / PDZ domain profile. / Domain present in PSD-95, Dlg, and ZO-1/2. / PDZ domain ... Zinc finger, C3HC4 type (RING finger) / PDZ domain / Pdz3 Domain / Zinc finger, RING-type, conserved site / Zinc finger RING-type signature. / Ring finger / PDZ domain / PDZ domain profile. / Domain present in PSD-95, Dlg, and ZO-1/2. / PDZ domain / PDZ superfamily / Zinc finger RING-type profile. / Zinc finger, RING-type / Zinc finger, RING/FYVE/PHD-type / Roll / Mainly Beta Similarity search - Domain/homologyBiological species HOMO SAPIENS (human)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.3 Å DetailsAuthors Roos, A.K. / Guo, K. / Burgess-Brown, N. / Yue, W.W. / Elkins, J.M. / Pike, A.C.W. / Filippakopoulos, P. / Arrowsmith, C.H. / Wikstom, M. / Edwards, A. ...Roos, A.K. / Guo, K. / Burgess-Brown, N. / Yue, W.W. / Elkins, J.M. / Pike, A.C.W. / Filippakopoulos, P. / Arrowsmith, C.H. / Wikstom, M. / Edwards, A. / von Delft, F. / Bountra, C. / Doyle, D. / Oppermann, U. CitationJournal : To be Published Title : Crystal Structure of the Second Pdz Domain of the Human Numb-Binding Protein 2Authors : Roos, A.K. / Guo, K. / Burgess-Brown, N. / Yue, W.W. / Elkins, J.M. / Pike, A.C.W. / Filippakopoulos, P. / Arrowsmith, C.H. / Wikstom, M. / Edwards, A. / von Delft, F. / Bountra, C. / Doyle, D. / Oppermann, U. History Deposition Jun 26, 2008 Deposition site : PDBE / Processing site : PDBERevision 1.0 Sep 16, 2008 Provider : repository / Type : Initial releaseRevision 1.1 May 8, 2011 Group : Version format complianceRevision 1.2 Jul 13, 2011 Group : Version format complianceRevision 1.3 Jan 24, 2018 Group : Database references / Structure summary / Category : audit_author / citation_author / Item : _audit_author.name / _citation_author.nameRevision 1.4 Dec 13, 2023 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / pdbx_struct_special_symmetry Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf
Show all Show less Remark 700 SHEET THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN ORDER TO REPRESENT THIS FEATURE IN ... SHEET THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN ORDER TO REPRESENT THIS FEATURE IN THE SHEET RECORDS BELOW, TWO SHEETS ARE DEFINED.