登録情報 データベース : PDB / ID : 2vm6 構造の表示 ダウンロードとリンクタイトル Human Bcl2-A1 in complex with Bim-BH3 peptide 要素BCL-2-LIKE PROTEIN 11 BCL-2-RELATED PROTEIN A1 詳細キーワード IMMUNE SYSTEM / B-CELL LYMPHOMA2 / ANTIAPOPTOTIC / BIM / BFL-1 / BCL2A1 / BCL-2A1 / MEMBRANE / APOPTOSIS機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
dynorphin receptor activity / Regulation of MITF-M-dependent genes involved in apoptosis / neuropeptide binding / mitochondrial fusion / BH domain binding / neuropeptide signaling pathway / Nuclear events stimulated by ALK signaling in cancer / extrinsic apoptotic signaling pathway in absence of ligand / sensory perception of pain / release of cytochrome c from mitochondria ... dynorphin receptor activity / Regulation of MITF-M-dependent genes involved in apoptosis / neuropeptide binding / mitochondrial fusion / BH domain binding / neuropeptide signaling pathway / Nuclear events stimulated by ALK signaling in cancer / extrinsic apoptotic signaling pathway in absence of ligand / sensory perception of pain / release of cytochrome c from mitochondria / intrinsic apoptotic signaling pathway in response to DNA damage / channel activity / mitochondrial outer membrane / neuron projection / negative regulation of apoptotic process / membrane / cytosol / cytoplasm 類似検索 - 分子機能 Bcl-2-related protein A1 / Kappa opioid receptor / Opioid receptor / Blc2-like / Apoptosis Regulator Bcl-x / Apoptosis regulator, Bcl-2, BH1 motif, conserved site / Apoptosis regulator, Bcl-2 family BH1 motif signature. / Apoptosis regulator, Bcl-2, BH2 motif, conserved site / Apoptosis regulator, Bcl-2 family BH2 motif signature. / Bcl-2 family ... Bcl-2-related protein A1 / Kappa opioid receptor / Opioid receptor / Blc2-like / Apoptosis Regulator Bcl-x / Apoptosis regulator, Bcl-2, BH1 motif, conserved site / Apoptosis regulator, Bcl-2 family BH1 motif signature. / Apoptosis regulator, Bcl-2, BH2 motif, conserved site / Apoptosis regulator, Bcl-2 family BH2 motif signature. / Bcl-2 family / BCL (B-Cell lymphoma); contains BH1, BH2 regions / Bcl2-like / Bcl-2, Bcl-2 homology region 1-3 / BCL2-like apoptosis inhibitors family profile. / Apoptosis regulator proteins, Bcl-2 family / Bcl-2-like superfamily / Serpentine type 7TM GPCR chemoreceptor Srsx / G-protein coupled receptors family 1 signature. / G protein-coupled receptor, rhodopsin-like / GPCR, rhodopsin-like, 7TM / G-protein coupled receptors family 1 profile. / 7 transmembrane receptor (rhodopsin family) / Orthogonal Bundle / Mainly Alpha 類似検索 - ドメイン・相同性 Kappa-type opioid receptor / Bcl-2-related protein A1 類似検索 - 構成要素生物種 HOMO SAPIENS (ヒト)手法 X線回折 / シンクロトロン / 多波長異常分散 / 解像度 : 2.2 Å 詳細データ登録者 Herman, M.D. / Lehtio, L. / Arrowsmith, C.H. / Berglund, H. / Busam, R.D. / Collins, R. / Dahlgren, L.G. / Edwards, A.M. / Flodin, S. / Flores, A. ...Herman, M.D. / Lehtio, L. / Arrowsmith, C.H. / Berglund, H. / Busam, R.D. / Collins, R. / Dahlgren, L.G. / Edwards, A.M. / Flodin, S. / Flores, A. / Graslund, S. / Hammarstrom, M. / Johansson, I. / Kallas, A. / Karlberg, T. / Kotenyova, T. / Moche, M. / Nilsson, M.E. / Nyman, T. / Persson, C. / Sagemark, J. / Svensson, L. / Thorsell, A.G. / Tresaugues, L. / van den Berg, S. / Weigelt, J. / Welin, M. / Nordlund, P. / Structural Genomics Consortium (SGC) 引用ジャーナル : FEBS Lett. / 年 : 2008タイトル : Completing the Family Portrait of the Anti- Apoptotic Bcl-2 Proteins: Crystal Structure of Human Bfl-1 in Complex with Bim.著者 : Herman, M.D. / Nyman, T. / Welin, M. / Lehtio, L. / Flodin, S. / Tresaugues, L. / Kotenyova, T. / Flores, A. / Nordlund, P. 履歴 登録 2008年1月23日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2008年2月5日 Provider : repository / タイプ : Initial release改定 1.1 2011年7月13日 Group : Advisory / Refinement description / Version format compliance改定 1.2 2019年9月25日 Group : Data collection / Experimental preparation / Otherカテゴリ : exptl_crystal_grow / pdbx_database_status / reflnsItem : _exptl_crystal_grow.method / _exptl_crystal_grow.temp ... _exptl_crystal_grow.method / _exptl_crystal_grow.temp / _pdbx_database_status.status_code_sf / _reflns.pdbx_Rmerge_I_obs 改定 1.3 2024年5月8日 Group : Data collection / Database references / カテゴリ : chem_comp_atom / chem_comp_bond / database_2Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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