Entry Database : PDB / ID : 2v2z Structure visualization Downloads & linksTitle IspE in complex with ADP and CDPME Components4-DIPHOSPHOCYTIDYL- ... Details Keywords TRANSFERASE / 4-DIPHOSPHOCYTIDYL-2C-METHYL-D-ERYTHRITOL / AQUIFEX AEOLICUS / NUCLEOTIDE-BINDING / ISOPRENE BIOSYNTHESIS / KINASE / ATP-BINDING / NON-MEVALONATEFunction / homology Function and homology informationFunction Domain/homology Component
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase / 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity / isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway / terpenoid biosynthetic process / phosphorylation / ATP binding Similarity search - Function 4-diphosphocytidyl-2C-methyl-D-erythritol kinase / GHMP kinase, C-terminal domain / GHMP kinase N-terminal domain / GHMP kinases N terminal domain / GHMP kinase, C-terminal domain superfamily / Ribosomal Protein S5; domain 2 - #10 / Ribosomal Protein S5; domain 2 / Ribosomal protein S5 domain 2-type fold, subgroup / Ribosomal protein S5 domain 2-type fold / Alpha-Beta Plaits ... 4-diphosphocytidyl-2C-methyl-D-erythritol kinase / GHMP kinase, C-terminal domain / GHMP kinase N-terminal domain / GHMP kinases N terminal domain / GHMP kinase, C-terminal domain superfamily / Ribosomal Protein S5; domain 2 - #10 / Ribosomal Protein S5; domain 2 / Ribosomal protein S5 domain 2-type fold, subgroup / Ribosomal protein S5 domain 2-type fold / Alpha-Beta Plaits / 2-Layer Sandwich / Alpha Beta Similarity search - Domain/homology ADENOSINE-5'-DIPHOSPHATE / 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL / 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase Similarity search - ComponentBiological species AQUIFEX AEOLICUS (bacteria)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.25 Å DetailsAuthors Sgraja, T. / Alphey, M.S. / Hunter, W.N. CitationJournal : FEBS J. / Year : 2008Title : Characterization of Aquifex Aeolicus 4-Diphosphocytidyl-2C-Methyl-D-Erythritol Kinase -Ligand Recognition in a Template for Antimicrobial Drug Discovery.Authors : Sgraja, T. / Alphey, M.S. / Ghilagaber, S. / Marquez, R. / Robertson, M.N. / Hemmings, J.L. / Lauw, S. / Rohdich, F. / Bacher, A. / Eisenreich, W. / Illarionova, V. / Hunter, W.N. History Deposition Jun 8, 2007 Deposition site : PDBE / Processing site : PDBERevision 1.0 Jun 19, 2007 Provider : repository / Type : Initial releaseRevision 1.1 May 8, 2011 Group : Version format complianceRevision 1.2 Jul 13, 2011 Group : Version format complianceRevision 1.3 May 8, 2024 Group : Data collection / Database references / OtherCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf
Show all Show less Remark 700 SHEET THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN ORDER TO REPRESENT THIS FEATURE IN ... SHEET THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN ORDER TO REPRESENT THIS FEATURE IN THE SHEET RECORDS BELOW, TWO SHEETS ARE DEFINED.