登録情報 データベース : PDB / ID : 2rsy 構造の表示 ダウンロードとリンクタイトル Solution structure of the SH2 domain of Csk in complex with a phosphopeptide from Cbp 要素Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 Tyrosine-protein kinase CSK 詳細キーワード TRANSFERASE/SIGNALING PROTEIN / SH2 domain / Csk / Cbp / solution structure / TRANSFERASE-SIGNALING PROTEIN complex機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
GAB1 signalosome / PD-1 signaling / Phosphorylation of CD3 and TCR zeta chains / Integrin signaling / negative regulation of Golgi to plasma membrane protein transport / RHOH GTPase cycle / regulation of Fc receptor mediated stimulatory signaling pathway / MAP2K and MAPK activation / negative regulation of low-density lipoprotein particle clearance / negative regulation of T cell activation ... GAB1 signalosome / PD-1 signaling / Phosphorylation of CD3 and TCR zeta chains / Integrin signaling / negative regulation of Golgi to plasma membrane protein transport / RHOH GTPase cycle / regulation of Fc receptor mediated stimulatory signaling pathway / MAP2K and MAPK activation / negative regulation of low-density lipoprotein particle clearance / negative regulation of T cell activation / transmembrane receptor protein tyrosine kinase adaptor activity / proline-rich region binding / adherens junction organization / negative regulation of bone resorption / negative regulation of phagocytosis / regulation of T cell activation / cellular response to peptide hormone stimulus / oligodendrocyte differentiation / plasma membrane => GO:0005886 / protein kinase A catalytic subunit binding / negative regulation of interleukin-6 production / SH2 domain binding / protein tyrosine kinase binding / non-specific protein-tyrosine kinase / non-membrane spanning protein tyrosine kinase activity / negative regulation of ERK1 and ERK2 cascade / cell-cell junction / protein phosphatase binding / protein tyrosine kinase activity / adaptive immune response / intracellular signal transduction / membrane raft / negative regulation of cell population proliferation / signal transduction / ATP binding / identical protein binding / metal ion binding / plasma membrane / cytoplasm 類似検索 - 分子機能 Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 / Phosphoprotein associated with glycosphingolipid-enriched / CSK-like, SH2 domain / SH2 domain / SHC Adaptor Protein / : / SH3 domain / SH2 domain / Src homology 2 (SH2) domain profile. / Src homology 2 domains ... Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 / Phosphoprotein associated with glycosphingolipid-enriched / CSK-like, SH2 domain / SH2 domain / SHC Adaptor Protein / : / SH3 domain / SH2 domain / Src homology 2 (SH2) domain profile. / Src homology 2 domains / SH2 domain / Src homology 3 domains / SH2 domain superfamily / SH3-like domain superfamily / Src homology 3 (SH3) domain profile. / SH3 domain / Tyrosine-protein kinase, catalytic domain / Tyrosine kinase, catalytic domain / Tyrosine protein kinases specific active-site signature. / Tyrosine-protein kinase, active site / Serine-threonine/tyrosine-protein kinase, catalytic domain / Protein tyrosine and serine/threonine kinase / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / 2-Layer Sandwich / Alpha Beta 類似検索 - ドメイン・相同性 Tyrosine-protein kinase CSK / Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 類似検索 - 構成要素生物種 Rattus norvegicus (ドブネズミ)手法 溶液NMR / simulated annealing , torsion angle dynamics 詳細Model details target function, model1 データ登録者 Tanaka, H. / Akagi, K. / Oneyama, C. / Tanaka, M. / Sasaki, Y. / Kanou, T. / Lee, Y. / Yokogawa, D. / Debenecker, M. / Nakagawa, A. ...Tanaka, H. / Akagi, K. / Oneyama, C. / Tanaka, M. / Sasaki, Y. / Kanou, T. / Lee, Y. / Yokogawa, D. / Debenecker, M. / Nakagawa, A. / Okada, M. / Ikegami, T. 引用ジャーナル : J.Biol.Chem. / 年 : 2013タイトル : Identification of a new interaction mode between the Src homology 2 domain of C-terminal Src kinase (Csk) and Csk-binding protein/phosphoprotein associated with glycosphingolipid microdomains.著者 : Tanaka, H. / Akagi, K. / Oneyama, C. / Tanaka, M. / Sasaki, Y. / Kanou, T. / Lee, Y.H. / Yokogawa, D. / Dobenecker, M.W. / Nakagawa, A. / Okada, M. / Ikegami, T. 履歴 登録 2012年9月10日 登録サイト : BMRB / 処理サイト : PDBJ改定 1.0 2013年4月10日 Provider : repository / タイプ : Initial release改定 1.1 2019年12月25日 Group : Data collection / Database references / Derived calculationsカテゴリ : citation / citation_author ... citation / citation_author / pdbx_nmr_software / pdbx_nmr_spectrometer / struct_conn / struct_ref_seq_dif Item : _citation.journal_volume / _citation.page_first ... _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_PubMed / _citation.title / _citation_author.name / _pdbx_nmr_software.name / _pdbx_nmr_spectrometer.model / _struct_conn.pdbx_leaving_atom_flag / _struct_ref_seq_dif.details
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