登録情報 | データベース: PDB / ID: 2ro1 |
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タイトル | NMR Solution Structures of Human KAP1 PHD finger-bromodomain |
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要素 | Transcription intermediary factor 1-beta |
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キーワード | TRANSCRIPTION / KAP / TIF / PHD finger / Bromodomain / SUMO / Acetylation / Alternative splicing / Metal-binding / Nucleus / Phosphoprotein / Repressor / Transcription regulation / Zinc / Zinc-finger |
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機能・相同性 | 機能・相同性情報
convergent extension involved in axis elongation / Krueppel-associated box domain binding / embryonic placenta morphogenesis / suppression of viral release by host / negative regulation of single stranded viral RNA replication via double stranded DNA intermediate / chromo shadow domain binding / genomic imprinting / Generic Transcription Pathway / SUMO transferase activity / DNA methylation-dependent constitutive heterochromatin formation ...convergent extension involved in axis elongation / Krueppel-associated box domain binding / embryonic placenta morphogenesis / suppression of viral release by host / negative regulation of single stranded viral RNA replication via double stranded DNA intermediate / chromo shadow domain binding / genomic imprinting / Generic Transcription Pathway / SUMO transferase activity / DNA methylation-dependent constitutive heterochromatin formation / protein sumoylation / epithelial to mesenchymal transition / heterochromatin / embryo implantation / SUMOylation of transcription cofactors / positive regulation of DNA repair / Regulation of endogenous retroelements by KRAB-ZFP proteins / promoter-specific chromatin binding / euchromatin / RING-type E3 ubiquitin transferase / positive regulation of protein import into nucleus / RNA polymerase II transcription regulator complex / HCMV Early Events / ubiquitin-protein transferase activity / ubiquitin protein ligase activity / transcription corepressor activity / chromatin organization / proteasome-mediated ubiquitin-dependent protein catabolic process / transcription coactivator activity / protein kinase activity / innate immune response / DNA repair / negative regulation of DNA-templated transcription / ubiquitin protein ligase binding / chromatin binding / positive regulation of DNA-templated transcription / negative regulation of transcription by RNA polymerase II / protein-containing complex / DNA binding / RNA binding / zinc ion binding / nucleoplasm / nucleus類似検索 - 分子機能 Transcription intermediary factor 1-beta / TIF1-beta, RING finger, HC subclass / : / : / zinc-RING finger domain / B-box, C-terminal / B-Box C-terminal domain / B-box zinc finger / B-Box-type zinc finger / B-box-type zinc finger ...Transcription intermediary factor 1-beta / TIF1-beta, RING finger, HC subclass / : / : / zinc-RING finger domain / B-box, C-terminal / B-Box C-terminal domain / B-box zinc finger / B-Box-type zinc finger / B-box-type zinc finger / Zinc finger B-box type profile. / Zinc finger, PHD-type, conserved site / PHD-finger / Zinc finger PHD-type signature. / Ring finger / Zinc finger PHD-type profile. / Zinc finger, PHD-finger / Zinc finger, PHD-type / PHD zinc finger / Zinc finger, FYVE/PHD-type / Zinc finger RING-type profile. / Zinc finger, RING-type / bromo domain / Bromodomain / Bromodomain (BrD) profile. / Bromodomain-like superfamily / Zinc finger, RING/FYVE/PHD-type類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | 溶液NMR / simulated annealing, torsion angle dynamics |
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データ登録者 | Zeng, L. / Yap, K.L. / Ivanov, A.V. / Wang, X. / Mujtaba, S. / Plotnikova, O. / Rauscher, F.J. |
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引用 | ジャーナル: Nat.Struct.Mol.Biol. / 年: 2008 タイトル: Structural insights into human KAP1 PHD finger-bromodomain and its role in gene silencing 著者: Zeng, L. / Yap, K.L. / Ivanov, A.V. / Wang, X. / Mujtaba, S. / Plotnikova, O. / Rauscher, F.J. / Zhou, M.M. |
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履歴 | 登録 | 2008年3月4日 | 登録サイト: BMRB / 処理サイト: PDBJ |
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改定 1.0 | 2008年5月20日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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改定 1.2 | 2022年3月16日 | Group: Data collection / Database references / Derived calculations カテゴリ: database_2 / pdbx_nmr_spectrometer ...database_2 / pdbx_nmr_spectrometer / pdbx_struct_assembly / pdbx_struct_oper_list / struct_conn / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_nmr_spectrometer.model / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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改定 1.3 | 2024年5月29日 | Group: Data collection / カテゴリ: chem_comp_atom / chem_comp_bond |
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