登録情報 データベース : PDB / ID : 2ot0 構造の表示 ダウンロードとリンクタイトル Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with a C-terminal peptide of Wiskott-Aldrich syndrome protein 要素Fructose-bisphosphate aldolase A Wiskott-Aldrich syndrome protein C-terminal peptide 詳細キーワード LYASE / complex / glycolysis / actin dynamics / hydrophobic pocket / WASp機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
regulation of T cell antigen processing and presentation / Cdc42 protein signal transduction / regulation of actin polymerization or depolymerization / GTPase regulator activity / negative regulation of Arp2/3 complex-mediated actin nucleation / actin filament-based movement / fructose-bisphosphate aldolase / fructose-bisphosphate aldolase activity / negative regulation of cell motility / actin polymerization or depolymerization ... regulation of T cell antigen processing and presentation / Cdc42 protein signal transduction / regulation of actin polymerization or depolymerization / GTPase regulator activity / negative regulation of Arp2/3 complex-mediated actin nucleation / actin filament-based movement / fructose-bisphosphate aldolase / fructose-bisphosphate aldolase activity / negative regulation of cell motility / actin polymerization or depolymerization / regulation of lamellipodium assembly / regulation of stress fiber assembly / M band / vesicle membrane / I band / negative regulation of stress fiber assembly / endosomal transport / RHOJ GTPase cycle / CDC42 GTPase cycle / Generation of second messenger molecules / RHO GTPases Activate WASPs and WAVEs / epidermis development / positive regulation of double-strand break repair via homologous recombination / phospholipase binding / phagocytic vesicle / actin filament polymerization / RAC1 GTPase cycle / T cell activation / glycolytic process / actin filament / FCGR3A-mediated phagocytosis / defense response / Regulation of actin dynamics for phagocytic cup formation / SH3 domain binding / cellular response to type II interferon / small GTPase binding / blood coagulation / cell-cell junction / actin cytoskeleton / site of double-strand break / actin binding / protein-containing complex assembly / protein homotetramerization / immune response / positive regulation of cell migration / protein kinase binding / positive regulation of transcription by RNA polymerase II / extracellular exosome / identical protein binding / nucleus / plasma membrane / cytosol 類似検索 - 分子機能 Actin nucleation-promoting factor WAS, C-terminal / WASP family, EVH1 domain / Wiskott Aldrich syndrome homology region 2 / WH2 motif / WH1/EVH1 domain / WH1 domain / WH1 domain profile. / WASP homology region 1 / WH2 domain / WH2 domain profile. ... Actin nucleation-promoting factor WAS, C-terminal / WASP family, EVH1 domain / Wiskott Aldrich syndrome homology region 2 / WH2 motif / WH1/EVH1 domain / WH1 domain / WH1 domain profile. / WASP homology region 1 / WH2 domain / WH2 domain profile. / Fructose-bisphosphate aldolase class-I active site / Fructose-bisphosphate aldolase class-I active site. / Fructose-bisphosphate aldolase, class-I / Fructose-bisphosphate aldolase class-I / CRIB domain superfamily / P21-Rho-binding domain / CRIB domain profile. / P21-Rho-binding domain / CRIB domain / Aldolase class I / PH-like domain superfamily / Aldolase-type TIM barrel / TIM Barrel / Alpha-Beta Barrel / Alpha Beta 類似検索 - ドメイン・相同性 Fructose-bisphosphate aldolase A / Actin nucleation-promoting factor WAS 類似検索 - 構成要素生物種 Oryctolagus cuniculus (ウサギ)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.05 Å 詳細データ登録者 St-Jean, M. / Izard, T. / Sygusch, J. 引用ジャーナル : J.Biol.Chem. / 年 : 2007タイトル : A hydrophobic pocket in the active site of glycolytic aldolase mediates interactions with wiskott-Aldrich syndrome protein.著者 : St-Jean, M. / Izard, T. / Sygusch, J. 履歴 登録 2007年2月7日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2007年2月27日 Provider : repository / タイプ : Initial release改定 1.1 2008年5月1日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance改定 1.3 2023年8月30日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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