登録情報 | データベース: PDB / ID: 2n00 |
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タイトル | NMR Solution structure of AIM2 PYD from Mus musculus |
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要素 | Interferon-inducible protein AIM2 |
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キーワード | DNA BINDING PROTEIN / AIM2 / PYD |
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機能・相同性 | 機能・相同性情報
Cytosolic sensors of pathogen-associated DNA / The AIM2 inflammasome / pyroptosome complex assembly / AIM2 inflammasome complex assembly / cysteine-type endopeptidase activator activity / AIM2 inflammasome complex / regulation of behavior / positive regulation of cysteine-type endopeptidase activity / pattern recognition receptor signaling pathway / pattern recognition receptor activity ...Cytosolic sensors of pathogen-associated DNA / The AIM2 inflammasome / pyroptosome complex assembly / AIM2 inflammasome complex assembly / cysteine-type endopeptidase activator activity / AIM2 inflammasome complex / regulation of behavior / positive regulation of cysteine-type endopeptidase activity / pattern recognition receptor signaling pathway / pattern recognition receptor activity / pyroptotic inflammatory response / T cell homeostasis / cellular response to interferon-beta / negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction / signaling adaptor activity / positive regulation of defense response to virus by host / tumor necrosis factor-mediated signaling pathway / activation of innate immune response / positive regulation of interleukin-1 beta production / brain development / neuron cellular homeostasis / positive regulation of inflammatory response / cellular response to xenobiotic stimulus / site of double-strand break / double-stranded DNA binding / defense response to virus / inflammatory response / innate immune response / DNA damage response / mitochondrion / nucleoplasm / identical protein binding / nucleus / cytoplasm / cytosol類似検索 - 分子機能 HIN-200/IF120x / HIN-200 family / HIN-200/IF120x domain / HIN-200 A and B domains profile. / DAPIN domain / DAPIN domain profile. / PAAD/DAPIN/Pyrin domain / Death Domain, Fas / PAAD/DAPIN/Pyrin domain / Death Domain, Fas ...HIN-200/IF120x / HIN-200 family / HIN-200/IF120x domain / HIN-200 A and B domains profile. / DAPIN domain / DAPIN domain profile. / PAAD/DAPIN/Pyrin domain / Death Domain, Fas / PAAD/DAPIN/Pyrin domain / Death Domain, Fas / Death-like domain superfamily / Nucleic acid-binding, OB-fold / Orthogonal Bundle / Mainly Alpha類似検索 - ドメイン・相同性 |
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生物種 | ![](img/tx_mammal.gif) Mus musculus (ハツカネズミ) |
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手法 | 溶液NMR / simulated annealing |
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Model details | lowest energy, model1 |
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データ登録者 | Hou, X. / Niu, X. |
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引用 | ジャーナル: Biochem.Biophys.Res.Commun. / 年: 2015 タイトル: The NMR solution structure of AIM2 PYD domain from Mus musculus reveals a distinct alpha 2-alpha 3 helix conformation from its human homologues 著者: Hou, X. / Niu, X. |
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履歴 | 登録 | 2015年3月1日 | 登録サイト: BMRB / 処理サイト: PDBJ |
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改定 1.0 | 2015年5月27日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2023年6月14日 | Group: Data collection / Database references / Other カテゴリ: database_2 / pdbx_database_status / pdbx_nmr_spectrometer Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_nmr_data / _pdbx_nmr_spectrometer.model |
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改定 1.2 | 2024年5月15日 | Group: Data collection / Database references / カテゴリ: chem_comp_atom / chem_comp_bond / database_2 / Item: _database_2.pdbx_DOI |
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