登録情報 | データベース: PDB / ID: 2m9w |
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タイトル | Solution NMR Structure of Transcription Factor GATA-4 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR4783B |
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要素 | Transcription factor GATA-4 |
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キーワード | TRANSCRIPTION / Structural Genomics / NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) / PSI-Biology / Protein Structure Initiative |
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機能・相同性 | 機能・相同性情報
atrial septum secundum morphogenesis / atrioventricular valve formation / transdifferentiation / embryonic heart tube anterior/posterior pattern specification / Formation of lateral plate mesoderm / cardiac right ventricle morphogenesis / intestinal epithelial cell differentiation / atrioventricular node development / co-SMAD binding / cell growth involved in cardiac muscle cell development ...atrial septum secundum morphogenesis / atrioventricular valve formation / transdifferentiation / embryonic heart tube anterior/posterior pattern specification / Formation of lateral plate mesoderm / cardiac right ventricle morphogenesis / intestinal epithelial cell differentiation / atrioventricular node development / co-SMAD binding / cell growth involved in cardiac muscle cell development / atrial septum morphogenesis / endocardial cushion development / cardiac muscle tissue regeneration / Transcriptional regulation of testis differentiation / cardiac ventricle morphogenesis / Physiological factors / atrial septum primum morphogenesis / embryonic foregut morphogenesis / atrioventricular canal development / YAP1- and WWTR1 (TAZ)-stimulated gene expression / Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) / endoderm development / Formation of definitive endoderm / positive regulation of BMP signaling pathway / response to vitamin A / regulation of cardiac muscle cell contraction / aortic valve morphogenesis / Cardiogenesis / ventricular septum development / DNA-binding transcription activator activity / negative regulation of cardiac muscle cell apoptotic process / NFAT protein binding / heart looping / negative regulation of apoptotic signaling pathway / positive regulation of vascular endothelial growth factor production / cell fate commitment / response to mechanical stimulus / negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway / negative regulation of autophagy / RNA polymerase II transcription regulatory region sequence-specific DNA binding / cellular response to glucose stimulus / wound healing / RNA polymerase II transcription regulator complex / positive regulation of angiogenesis / male gonad development / sequence-specific double-stranded DNA binding / cell-cell signaling / Factors involved in megakaryocyte development and platelet production / DNA-binding transcription activator activity, RNA polymerase II-specific / RNA polymerase II-specific DNA-binding transcription factor binding / sequence-specific DNA binding / nuclear body / transcription cis-regulatory region binding / DNA-binding transcription factor activity, RNA polymerase II-specific / response to xenobiotic stimulus / RNA polymerase II cis-regulatory region sequence-specific DNA binding / regulation of DNA-templated transcription / chromatin / protein kinase binding / positive regulation of DNA-templated transcription / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / DNA binding / zinc ion binding / nucleoplasm / nucleus類似検索 - 分子機能 GATA-type transcription activator, N-terminal / Transcription factor GATA-4/5/6 / GATA-type transcription activator, N-terminal / Transcription factor GATA / GATA-type zinc finger domain. / GATA-type zinc finger domain profile. / zinc finger binding to DNA consensus sequence [AT]GATA[AG] / GATA zinc finger / Zinc finger, GATA-type / Erythroid Transcription Factor GATA-1, subunit A ...GATA-type transcription activator, N-terminal / Transcription factor GATA-4/5/6 / GATA-type transcription activator, N-terminal / Transcription factor GATA / GATA-type zinc finger domain. / GATA-type zinc finger domain profile. / zinc finger binding to DNA consensus sequence [AT]GATA[AG] / GATA zinc finger / Zinc finger, GATA-type / Erythroid Transcription Factor GATA-1, subunit A / Erythroid Transcription Factor GATA-1; Chain A / Zinc finger, NHR/GATA-type / 2-Layer Sandwich / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | 溶液NMR / simulated annealing |
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Model details | lowest energy, model1 |
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データ登録者 | Xu, X. / Eletsky, A. / Lee, D. / Kohn, E. / Janjua, H. / Xiao, R. / Acton, T.B. / Everett, J.K. / Montelione, G.T. / Szyperski, T. / Northeast Structural Genomics Consortium (NESG) |
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引用 | ジャーナル: To be Published タイトル: Solution NMR Structure of a Transcription Factor GATA-4 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR4783B 著者: Xu, X. / Eletsky, A. / Lee, D. / Kohn, E. / Janjua, H. / Xiao, R. / Acton, T. / Everett, J.K. / Montelione, G.T. / Szyperski, T. |
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履歴 | 登録 | 2013年6月20日 | 登録サイト: BMRB / 処理サイト: RCSB |
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改定 1.0 | 2013年7月10日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2023年6月14日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Other カテゴリ: database_2 / pdbx_database_status ...database_2 / pdbx_database_status / pdbx_nmr_software / pdbx_struct_conn_angle / struct_conn / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_nmr_data / _pdbx_nmr_software.name / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_seq_id / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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改定 1.2 | 2024年5月15日 | Group: Data collection / Database references / カテゴリ: chem_comp_atom / chem_comp_bond / database_2 / Item: _database_2.pdbx_DOI |
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