登録情報 データベース : PDB / ID : 2m8r 構造の表示 ダウンロードとリンクタイトル Pre-Fusion Solution NMR Structure of Neuronal SNARE Syntaxin 1A 要素Syntaxin-1A 詳細 キーワード MEMBRANE PROTEIN / syntaxin / SNARE / Prefusion機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
myosin head/neck binding / Other interleukin signaling / synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex / synaptobrevin 2-SNAP-25-syntaxin-1a complex / synaptic vesicle fusion to presynaptic active zone membrane / synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex / Glutamate Neurotransmitter Release Cycle / positive regulation of norepinephrine secretion / Norepinephrine Neurotransmitter Release Cycle / Acetylcholine Neurotransmitter Release Cycle ... myosin head/neck binding / Other interleukin signaling / synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex / synaptobrevin 2-SNAP-25-syntaxin-1a complex / synaptic vesicle fusion to presynaptic active zone membrane / synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex / Glutamate Neurotransmitter Release Cycle / positive regulation of norepinephrine secretion / Norepinephrine Neurotransmitter Release Cycle / Acetylcholine Neurotransmitter Release Cycle / positive regulation of catecholamine secretion / Serotonin Neurotransmitter Release Cycle / GABA synthesis, release, reuptake and degradation / regulation of synaptic vesicle priming / Dopamine Neurotransmitter Release Cycle / regulated exocytosis / synaptic vesicle docking / response to gravity / Insertion of tail-anchored proteins into the endoplasmic reticulum membrane / positive regulation of calcium ion-dependent exocytosis / vesicle docking / chloride channel inhibitor activity / secretion by cell / SNARE complex / SNAP receptor activity / regulation of exocytosis / LGI-ADAM interactions / hormone secretion / calcium-ion regulated exocytosis / actomyosin / ATP-dependent protein binding / protein localization to membrane / neurotransmitter transport / insulin secretion / SNARE complex assembly / positive regulation of neurotransmitter secretion / myosin binding / exocytosis / positive regulation of exocytosis / synaptic vesicle exocytosis / modulation of excitatory postsynaptic potential / positive regulation of excitatory postsynaptic potential / protein sumoylation / synaptic vesicle endocytosis / endomembrane system / calcium channel inhibitor activity / presynaptic active zone membrane / acrosomal vesicle / SNARE binding / secretory granule / intracellular protein transport / postsynaptic density membrane / Schaffer collateral - CA1 synapse / kinase binding / synaptic vesicle membrane / calcium-dependent protein binding / synaptic vesicle / presynapse / presynaptic membrane / protein-macromolecule adaptor activity / nuclear membrane / transmembrane transporter binding / postsynaptic density / neuron projection / axon / glutamatergic synapse / synapse / protein-containing complex binding / protein-containing complex / identical protein binding / membrane / plasma membrane 類似検索 - 分子機能 Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #110 / Syntaxin / Syntaxin N-terminal domain / Syntaxin, N-terminal domain / Syntaxin / SNARE domain / Syntaxin/epimorphin, conserved site / Syntaxin / epimorphin family signature. / SNARE / Helical region found in SNAREs ... Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #110 / Syntaxin / Syntaxin N-terminal domain / Syntaxin, N-terminal domain / Syntaxin / SNARE domain / Syntaxin/epimorphin, conserved site / Syntaxin / epimorphin family signature. / SNARE / Helical region found in SNAREs / t-SNARE coiled-coil homology domain profile. / Target SNARE coiled-coil homology domain / Single alpha-helices involved in coiled-coils or other helix-helix interfaces / Up-down Bundle / Mainly Alpha 類似検索 - ドメイン・相同性生物種 Rattus norvegicus (ドブネズミ)手法 溶液NMR / distance geometry , simulated annealing 詳細Model details lowest energy, model20 データ登録者 Liang, B. / Kiessling, V. / Tamm, L.K. 引用ジャーナル : Proc.Natl.Acad.Sci.USA / 年 : 2013タイトル : Prefusion structure of syntaxin-1A suggests pathway for folding into neuronal trans-SNARE complex fusion intermediate.著者 : Liang, B. / Kiessling, V. / Tamm, L.K. 履歴 登録 2013年5月24日 登録サイト : BMRB / 処理サイト : RCSB改定 1.0 2013年11月20日 Provider : repository / タイプ : Initial release改定 1.1 2013年11月27日 Group : Database references改定 1.2 2013年12月11日 Group : Database references改定 1.3 2024年5月1日 Group : Data collection / Database referencesカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_nmr_software / pdbx_nmr_spectrometer / struct_ref_seq_dif Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_nmr_software.name / _pdbx_nmr_spectrometer.model / _struct_ref_seq_dif.details
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