Entry Database : PDB / ID : 2ldu Structure visualization Downloads & linksTitle Solution NMR Structure of Heat shock factor protein 1 DNA binding domain from homo sapiens, Northeast Structural Genomics Consortium Target HR3023C ComponentsHeat shock factor protein 1 Details Keywords CHAPERONE / Structural Genomics / NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) / DNA-binding / PSI-Biology / Protein Structure InitiativeFunction / homology Function and homology informationFunction Domain/homology Component
cellular response to nitroglycerin / embryonic process involved in female pregnancy / sequence-specific single stranded DNA binding / cellular response to diamide / response to hypobaric hypoxia / negative regulation of double-strand break repair via nonhomologous end joining / cellular response to L-glutamine / positive regulation of stress granule assembly / positive regulation of apoptotic DNA fragmentation / response to peptide ... cellular response to nitroglycerin / embryonic process involved in female pregnancy / sequence-specific single stranded DNA binding / cellular response to diamide / response to hypobaric hypoxia / negative regulation of double-strand break repair via nonhomologous end joining / cellular response to L-glutamine / positive regulation of stress granule assembly / positive regulation of apoptotic DNA fragmentation / response to peptide / cellular response to sodium arsenite / translation elongation factor binding / negative regulation of inclusion body assembly / nuclear stress granule / female meiotic nuclear division / positive regulation of macrophage differentiation / positive regulation of inclusion body assembly / positive regulation of multicellular organism growth / pronucleus / cellular response to potassium ion / protein folding chaperone complex / negative regulation of cardiac muscle cell apoptotic process / RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding / STAT family protein binding / response to psychosocial stress / mitotic spindle pole / response to testosterone / cellular response to cadmium ion / cellular response to angiotensin / negative regulation of tumor necrosis factor production / general transcription initiation factor binding / HSF1-dependent transactivation / Regulation of HSF1-mediated heat shock response / cellular response to unfolded protein / mRNA transport / Mitochondrial unfolded protein response (UPRmt) / HSF1 activation / embryonic placenta development / Attenuation phase / negative regulation of protein-containing complex assembly / heterochromatin / regulation of cellular response to heat / heat shock protein binding / response to nutrient / positive regulation of mitotic cell cycle / cellular response to copper ion / positive regulation of apoptotic signaling pathway / epithelial cell proliferation / response to activity / cellular response to estradiol stimulus / Hsp90 protein binding / chromatin DNA binding / promoter-specific chromatin binding / euchromatin / cellular response to gamma radiation / defense response / PML body / kinetochore / Aggrephagy / DNA-binding transcription repressor activity, RNA polymerase II-specific / cellular response to xenobiotic stimulus / cellular response to hydrogen peroxide / mRNA processing / negative regulation of epithelial cell proliferation / sequence-specific double-stranded DNA binding / MAPK cascade / positive regulation of cold-induced thermogenesis / cellular response to heat / cellular response to lipopolysaccharide / protein-containing complex assembly / DNA-binding transcription activator activity, RNA polymerase II-specific / spermatogenesis / sequence-specific DNA binding / DNA-binding transcription factor activity, RNA polymerase II-specific / transcription cis-regulatory region binding / RNA polymerase II cis-regulatory region sequence-specific DNA binding / DNA-binding transcription factor activity / protein heterodimerization activity / ribonucleoprotein complex / DNA repair / centrosome / positive regulation of gene expression / regulation of transcription by RNA polymerase II / protein kinase binding / chromatin / perinuclear region of cytoplasm / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / DNA binding / nucleoplasm / identical protein binding / nucleus / cytosol / cytoplasm Similarity search - Function Vertebrate heat shock transcription factor, C-terminal domain / Vertebrate heat shock transcription factor / HSF-type DNA-binding domain signature. / Heat shock factor (HSF)-type, DNA-binding / HSF-type DNA-binding / heat shock factor / Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain / Arc Repressor Mutant, subunit A / Winged helix DNA-binding domain superfamily / Winged helix-like DNA-binding domain superfamily ... Vertebrate heat shock transcription factor, C-terminal domain / Vertebrate heat shock transcription factor / HSF-type DNA-binding domain signature. / Heat shock factor (HSF)-type, DNA-binding / HSF-type DNA-binding / heat shock factor / Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain / Arc Repressor Mutant, subunit A / Winged helix DNA-binding domain superfamily / Winged helix-like DNA-binding domain superfamily / Orthogonal Bundle / Mainly Alpha Similarity search - Domain/homologyBiological species Homo sapiens (human)Method SOLUTION NMR / distance geometry , molecular dynamics , simulated annealing , torsion angle dynamics DetailsModel details lowest energy, model 1 Authors Liu, G. / Xiao, R. / Ciccosanti, C. / Janjua, H. / Acton, T.B. / Lee, H. / Wang, H.B. / Huang, Y.B. / Everett, J.K. / Montelione, G.T. / Northeast Structural Genomics Consortium (NESG) CitationJournal : To be Published Title : Northeast Structural Genomics Consortium Target HR3023CAuthors : Liu, G. / Xiao, R. / Ciccosanti, C. / Janjua, H. / Acton, T.B. / Wang, H. / Lee, H.B. / Huang, Y.T. / Everett, J.K. / Montelione, G.T. History Deposition Jun 1, 2011 Deposition site : BMRB / Processing site : RCSBRevision 1.0 Jul 6, 2011 Provider : repository / Type : Initial releaseRevision 1.1 Jul 13, 2011 Group : Version format complianceRevision 1.2 Feb 22, 2012 Group : Structure summaryRevision 1.3 Jun 14, 2023 Group : Data collection / Database references / OtherCategory : database_2 / pdbx_database_status ... database_2 / pdbx_database_status / pdbx_nmr_software / pdbx_nmr_spectrometer / struct_ref_seq_dif Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_nmr_data / _pdbx_nmr_software.name / _pdbx_nmr_spectrometer.model / _struct_ref_seq_dif.details Revision 1.4 May 15, 2024 Group : Data collection / Database references / Category : chem_comp_atom / chem_comp_bond / database_2 / Item : _database_2.pdbx_DOI
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