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- PDB-2l95: Solution Structure of Cytotoxic T-Lymphocyte Antigent-2(Ctla prot... -
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Open data
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Basic information
Entry | Database: PDB / ID: 2l95 | ||||||
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Title | Solution Structure of Cytotoxic T-Lymphocyte Antigent-2(Ctla protein), Crammer at pH 6.0 | ||||||
![]() | Crammer | ||||||
![]() | HYDROLASE / CRAMMER / CYSTEINE PROTEINASE INHIBITOR / INTRINSIC DISORDER P CTLA-2-LIKE PROTEIN | ||||||
Function / homology | ![]() inhibition of cysteine-type endopeptidase activity / short-term memory / cysteine-type endopeptidase inhibitor activity / endomembrane system / long-term memory / lysosome / hydrolase activity Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | SOLUTION NMR / SIMULATED ANNEALING, MOLECULAR DYNAMICS | ||||||
Model details | lowest energy, model 1 | ||||||
![]() | Tseng, T.S. / Cheng, C.S. / Liu, Y.N. / Lyu, P.C. | ||||||
![]() | ![]() Title: A molten globule-to-ordered structure transition of Drosophila melanogaster crammer is required for its ability to inhibit cathepsin. Authors: Tseng, T.S. / Cheng, C.S. / Chen, D.J. / Shih, M.F. / Liu, Y.N. / Hsu, S.T. / Lyu, P.C. | ||||||
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 263.2 KB | Display | ![]() |
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PDB format | ![]() | 218.2 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 403.8 KB | Display | ![]() |
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Full document | ![]() | 484.1 KB | Display | |
Data in XML | ![]() | 31.8 KB | Display | |
Data in CIF | ![]() | 42.8 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Similar structure data | |
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Links
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Assembly
Deposited unit | ![]()
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NMR ensembles |
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Components
#1: Protein | Mass: 9595.816 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() References: UniProt: A1ZBK7, Hydrolases; Acting on peptide bonds (peptidases) |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||||||||||||||||||||||||||||||||||||||
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NMR experiment |
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Sample preparation
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Sample |
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Sample conditions | pH: 6 / Pressure: ambient / Temperature: 298 K |
-NMR measurement
NMR spectrometer | Type: BRUKER AMX / Manufacturer: Bruker / Model: AMX / Field strength: 600 MHz |
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Processing
NMR software |
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Refinement | Method: SIMULATED ANNEALING, MOLECULAR DYNAMICS / Software ordinal: 1 | ||||||||||||||||||||||||||||||||||||||||||||||||
NMR representative | Selection criteria: lowest energy | ||||||||||||||||||||||||||||||||||||||||||||||||
NMR ensemble | Conformer selection criteria: structures with the lowest energy Conformers calculated total number: 500 / Conformers submitted total number: 10 / Representative conformer: 1 |