+Open data
-Basic information
Entry | Database: PDB / ID: 2kw1 | ||||||
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Title | Solution structure of CTD | ||||||
Components | Fas apoptotic inhibitory molecule 1 | ||||||
Keywords | APOPTOSIS / beta-sheets | ||||||
Function / homology | Function and homology information positive regulation of neurogenesis / canonical NF-kappaB signal transduction / negative regulation of extrinsic apoptotic signaling pathway via death domain receptors / apoptotic process / cytoplasm Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | SOLUTION NMR / simulated annealing | ||||||
Model details | lowest energy, model 3 | ||||||
Authors | Ma, S. / Zheng, X. / Jin, C. | ||||||
Citation | Journal: To be Published Title: Solution structure of CTD Authors: Ma, S. / Zheng, X. / Jin, C. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 2kw1.cif.gz | 540.7 KB | Display | PDBx/mmCIF format |
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PDB format | pdb2kw1.ent.gz | 455.7 KB | Display | PDB format |
PDBx/mmJSON format | 2kw1.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 2kw1_validation.pdf.gz | 340 KB | Display | wwPDB validaton report |
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Full document | 2kw1_full_validation.pdf.gz | 426.9 KB | Display | |
Data in XML | 2kw1_validation.xml.gz | 24.1 KB | Display | |
Data in CIF | 2kw1_validation.cif.gz | 43.4 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/kw/2kw1 ftp://data.pdbj.org/pub/pdb/validation_reports/kw/2kw1 | HTTPS FTP |
-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein | Mass: 10079.250 Da / Num. of mol.: 1 / Fragment: UNP residues 91-179 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Homo sapiens (human) / Production host: Escherichia coli (E. coli) / References: UniProt: Q9NVQ4 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||||||||||||||||||||||||||||||||||
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NMR experiment |
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-Sample preparation
Details | Contents: 10mM HEPES; 50mM sodium chloride; 5mM DTT; 10% D2O; 0.01% DSS; 90% H2O/10% D2O Solvent system: 90% H2O/10% D2O | ||||||||||||||||||
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Sample |
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Sample conditions | pH: 7.0 / Pressure: ambient / Temperature: 298 K |
-NMR measurement
NMR spectrometer | Type: Bruker Avance / Manufacturer: Bruker / Model: AVANCE / Field strength: 600 MHz |
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-Processing
NMR software | Name: Amber Developer: Case, Darden, Cheatham, III, Simmerling, Wang, Duke, Luo, and Kollm Classification: refinement |
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Refinement | Method: simulated annealing / Software ordinal: 1 |
NMR representative | Selection criteria: lowest energy |
NMR ensemble | Conformer selection criteria: structures with the lowest energy Conformers calculated total number: 100 / Conformers submitted total number: 20 / Representative conformer: 3 |