Entry Database : PDB / ID : 5c6r Structure visualization Downloads & linksTitle Crystal structure of PH domain of ASAP1 ComponentsArf-GAP Details Keywords SIGNALING PROTEIN / PH domain / ASPA1Function / homology Function and homology informationFunction Domain/homology Component
VxPx cargo-targeting to cilium / positive regulation of membrane tubulation / negative regulation of dendritic spine development / protein localization to cilium / podosome / regulation of postsynapse organization / phosphatidylserine binding / phosphatidylinositol-3,4,5-trisphosphate binding / cilium assembly / phosphatidylinositol-4,5-bisphosphate binding ... VxPx cargo-targeting to cilium / positive regulation of membrane tubulation / negative regulation of dendritic spine development / protein localization to cilium / podosome / regulation of postsynapse organization / phosphatidylserine binding / phosphatidylinositol-3,4,5-trisphosphate binding / cilium assembly / phosphatidylinositol-4,5-bisphosphate binding / GTPase activator activity / trans-Golgi network membrane / dendritic spine / Golgi membrane / glutamatergic synapse / metal ion binding / cytosol Similarity search - Function ASAP1, BAR domain / ASAP1, SH3 domain / ASAP, PH domain / Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein / BAR domain of APPL family / Arf GTPase activating protein / ArfGAP domain superfamily / Putative GTPase activating protein for Arf / ARF GTPase-activating proteins domain profile. / Putative GTP-ase activating proteins for the small GTPase, ARF ... ASAP1, BAR domain / ASAP1, SH3 domain / ASAP, PH domain / Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein / BAR domain of APPL family / Arf GTPase activating protein / ArfGAP domain superfamily / Putative GTPase activating protein for Arf / ARF GTPase-activating proteins domain profile. / Putative GTP-ase activating proteins for the small GTPase, ARF / BAR domain / ARFGAP/RecO-like zinc finger / AH/BAR domain superfamily / Variant SH3 domain / Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) / PH-domain like / PH domain / PH domain profile. / Pleckstrin homology domain. / Pleckstrin homology domain / Ankyrin repeats (3 copies) / Ankyrin repeat profile. / Ankyrin repeat region circular profile. / ankyrin repeats / Ankyrin repeat / Ankyrin repeat-containing domain superfamily / Src homology 3 domains / SH3-like domain superfamily / Src homology 3 (SH3) domain profile. / SH3 domain / PH-like domain superfamily / Roll / Mainly Beta Similarity search - Domain/homologyBiological species Mus musculus (house mouse)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.8 Å DetailsAuthors Xia, D. / Tang, W.K. CitationJournal : Structure / Year : 2015Title : Molecular Basis for Cooperative Binding of Anionic Phospholipids to the PH Domain of the Arf GAP ASAP1.Authors : Jian, X. / Tang, W.K. / Zhai, P. / Roy, N.S. / Luo, R. / Gruschus, J.M. / Yohe, M.E. / Chen, P.W. / Li, Y. / Byrd, R.A. / Xia, D. / Randazzo, P.A. History Deposition Jun 23, 2015 Deposition site : RCSB / Processing site : RCSBRevision 1.0 Oct 7, 2015 Provider : repository / Type : Initial releaseRevision 1.1 Nov 18, 2015 Group : Database referencesRevision 1.2 Sep 27, 2023 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / citation / database_2 / pdbx_initial_refinement_model / pdbx_struct_oper_list / struct_ncs_dom_lim Item : _citation.journal_id_CSD / _database_2.pdbx_DOI ... _citation.journal_id_CSD / _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_oper_list.symmetry_operation / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id
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