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- PDB-2ktx: COMPLETE KALIOTOXIN FROM ANDROCTONUS MAURETANICUS MAURETANICUS, N... -
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Open data
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Basic information
Entry | Database: PDB / ID: 2ktx | ||||||
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Title | COMPLETE KALIOTOXIN FROM ANDROCTONUS MAURETANICUS MAURETANICUS, NMR, 18 STRUCTURES | ||||||
![]() | KALIOTOXIN | ||||||
![]() | NEUROTOXIN / POTASSIUM CHANNEL INHIBITOR | ||||||
Function / homology | Scorpion short toxins signature. / Scorpion short chain toxin, potassium channel inhibitor / Scorpion short toxin, BmKK2 / Knottin, scorpion toxin-like superfamily / ion channel inhibitor activity / potassium channel regulator activity / toxin activity / extracellular region / Potassium channel toxin alpha-KTx 3.1![]() | ||||||
Biological species | ![]() | ||||||
Method | SOLUTION NMR / DISTANCE GEOMETRY, SIMULATED ANNEALING | ||||||
![]() | Gairi, M. / Romi, R. / Fernandez, I. / Rochat, H. / Martin-Eauclaire, M.-F. / Van Rietschtoten, J. / Pons, M. / Giralt, E. | ||||||
![]() | ![]() Title: 3D structure of kaliotoxin: is residue 34 a key for channel selectivity? Authors: Gairi, M. / Romi, R. / Fernandez, I. / Rochat, H. / Martin-Eauclaire, M.F. / Van Rietschoten, J. / Pons, M. / Giralt, E. #1: ![]() Title: Kaliotoxin, a Novel Peptidyl Inhibitor of Neuronal Bk-Type Ca(2+)-Activated K+ Channels Characterized from Androctonus Mauretanicus Mauretanicus Venom Authors: Crest, M. / Jacquet, G. / Gola, M. / Zerrouk, H. / Benslimane, A. / Rochat, H. / Mansuelle, P. / Martin-Eauclaire, M.F. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 199.9 KB | Display | ![]() |
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PDB format | ![]() | 173 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
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-Validation report
Summary document | ![]() | 355.3 KB | Display | ![]() |
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Full document | ![]() | 420 KB | Display | |
Data in XML | ![]() | 11.7 KB | Display | |
Data in CIF | ![]() | 19.9 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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NMR ensembles |
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Components
#1: Protein/peptide | Mass: 4165.052 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() Species: Androctonus mauretanicus / Strain: mauretanicus / References: UniProt: P24662 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||
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NMR experiment |
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Sample preparation
Sample conditions | pH: 5.5 / Temperature: 298 K |
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Crystal grow | *PLUS Method: other / Details: NMR |
-NMR measurement
NMR spectrometer | Type: Bruker AVANCE DMX500 / Manufacturer: Bruker / Model: AVANCE DMX500 / Field strength: 500 MHz |
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Processing
NMR software |
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Refinement | Method: DISTANCE GEOMETRY, SIMULATED ANNEALING / Software ordinal: 1 Details: DGII ALSO WAS USED. REFINEMENT DETAILS CAN BE FOUND IN THE JRNL CITATION ABOVE. | ||||||||||||
NMR ensemble | Conformer selection criteria: TOTAL ENERGY/DISTANCE VIOLATIONS Conformers calculated total number: 35 / Conformers submitted total number: 18 |