登録情報 データベース : PDB / ID : 2klz 構造の表示 ダウンロードとリンクタイトル Solution Structure of the Tandem UIM Domain of Ataxin-3 Complexed with Ubiquitin 要素Ataxin-3 詳細 キーワード HYDROLASE / UIM / Ataxin-3 / Ubiquitin-binding / Neurodegeneration / Nucleus / Phosphoprotein / Spinocerebellar ataxia / Transcription / Transcription regulation機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
protein localization to cytosolic proteasome complex / regulation of cell-substrate adhesion / positive regulation of ERAD pathway / monoubiquitinated protein deubiquitination / intermediate filament cytoskeleton organization / protein K48-linked deubiquitination / nuclear inclusion body / positive regulation of ubiquitin-dependent protein catabolic process / protein K63-linked deubiquitination / cellular response to misfolded protein ... protein localization to cytosolic proteasome complex / regulation of cell-substrate adhesion / positive regulation of ERAD pathway / monoubiquitinated protein deubiquitination / intermediate filament cytoskeleton organization / protein K48-linked deubiquitination / nuclear inclusion body / positive regulation of ubiquitin-dependent protein catabolic process / protein K63-linked deubiquitination / cellular response to misfolded protein / K48-linked deubiquitinase activity / K63-linked deubiquitinase activity / protein quality control for misfolded or incompletely synthesized proteins / FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes / negative regulation of TORC1 signaling / cellular response to amino acid starvation / Josephin domain DUBs / mitochondrial membrane / nucleotide-excision repair / nuclear matrix / microtubule cytoskeleton organization / nervous system development / cellular response to heat / ATPase binding / actin cytoskeleton organization / ubiquitin-dependent protein catabolic process / chemical synaptic transmission / proteasome-mediated ubiquitin-dependent protein catabolic process / ubiquitinyl hydrolase 1 / cysteine-type deubiquitinase activity / mitochondrial matrix / lysosomal membrane / ubiquitin protein ligase binding / synapse / nucleolus / nucleoplasm / identical protein binding / nucleus / plasma membrane / cytoplasm / cytosol 類似検索 - 分子機能 Unstructured region C-term to UIM in Ataxin3 / Machado-Joseph disease protein / Josephin domain / Josephin / Josephin domain profile. / Josephin / Ubiquitin interaction motif / Ubiquitin-interacting motif. / Ubiquitin interacting motif / Ubiquitin-interacting motif (UIM) domain profile. 類似検索 - ドメイン・相同性生物種 Homo sapiens (ヒト)手法 溶液NMR / torsion angle dynamics 詳細Model details lowest energy, model 1 データ登録者 Zhou, C. / Song, A. / Lin, D. / Hu, H. 引用ジャーナル : To be Published タイトル : Solution Structure of the Tandem UIM Domain of Ataxin-3 Complexed with Ubiquitin著者 : Song, A. / Zhou, C. / Gao, H. / Zhou, Z. / Fu, Q. / Hong, J. / Lin, D. / Hu, H. 履歴 登録 2009年7月12日 登録サイト : BMRB / 処理サイト : PDBJ改定 1.0 2010年7月28日 Provider : repository / タイプ : Initial release改定 1.1 2011年7月13日 Group : Version format compliance改定 1.2 2020年2月26日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other カテゴリ : database_2 / pdbx_database_status ... database_2 / pdbx_database_status / pdbx_nmr_software / pdbx_struct_assembly / pdbx_struct_oper_list / struct_ref_seq_dif Item : _pdbx_database_status.status_code_cs / _pdbx_nmr_software.name / _struct_ref_seq_dif.details改定 1.3 2023年6月14日 Group : Database references / Other / カテゴリ : database_2 / pdbx_database_statusItem : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_nmr_data改定 1.4 2024年5月15日 Group : Data collection / Database references / カテゴリ : chem_comp_atom / chem_comp_bond / database_2 / Item : _database_2.pdbx_DOI
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