登録情報 | データベース: PDB / ID: 2kem |
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タイトル | Extended structure of citidine deaminase domain of APOBEC3G |
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要素 | DNA dC->dU-editing enzyme APOBEC-3G |
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キーワード | HYDROLASE / helix / sheet / zinc / Alternative splicing / Antiviral defense / Cytoplasm / Host-virus interaction / Metal-binding / Nucleus / Polymorphism / Ubl conjugation |
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機能・相同性 | 機能・相同性情報
apolipoprotein B mRNA editing enzyme complex / dCTP deaminase activity / cytidine deamination / base conversion or substitution editing / single-stranded DNA cytosine deaminase / DNA cytosine deamination / : / cytidine to uridine editing / cytidine deaminase activity / negative regulation of viral process ...apolipoprotein B mRNA editing enzyme complex / dCTP deaminase activity / cytidine deamination / base conversion or substitution editing / single-stranded DNA cytosine deaminase / DNA cytosine deamination / : / cytidine to uridine editing / cytidine deaminase activity / negative regulation of viral process / negative regulation of single stranded viral RNA replication via double stranded DNA intermediate / : / retrotransposon silencing / negative regulation of viral genome replication / APOBEC3G mediated resistance to HIV-1 infection / positive regulation of defense response to virus by host / Vif-mediated degradation of APOBEC3G / P-body / defense response to virus / ribonucleoprotein complex / innate immune response / RNA binding / zinc ion binding / identical protein binding / nucleus / cytoplasm / cytosol類似検索 - 分子機能 APOBEC-like C-terminal domain / Novel AID APOBEC clade 2 / : / APOBEC/CMP deaminase, zinc-binding / Cytidine and deoxycytidylate deaminases zinc-binding region signature. / Cytidine and deoxycytidylate deaminase domain / Cytidine and deoxycytidylate deaminases domain profile. / Cytidine deaminase-like類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | 溶液NMR / simulated annealing |
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Model details | lowest energy, model 1 |
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データ登録者 | Harjes, E. / Gross, P.J. / Chen, K. / Lu, Y. / Shindo, K. / Nowarski, R. / Gross, J.D. / Kotler, M. / Harris, R.S. / Matsuo, H. |
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引用 | ジャーナル: J.Mol.Biol. / 年: 2009 タイトル: An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model 著者: Harjes, E. / Gross, P.J. / Chen, K.M. / Lu, Y. / Shindo, K. / Nowarski, R. / Gross, J.D. / Kotler, M. / Harris, R.S. / Matsuo, H. |
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履歴 | 登録 | 2009年1月30日 | 登録サイト: BMRB / 処理サイト: PDBJ |
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改定 1.0 | 2009年6月2日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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改定 1.2 | 2021年11月10日 | Group: Data collection / Database references / Derived calculations カテゴリ: database_2 / pdbx_nmr_spectrometer ...database_2 / pdbx_nmr_spectrometer / pdbx_struct_assembly / pdbx_struct_oper_list / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_nmr_spectrometer.model / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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改定 1.3 | 2024年5月29日 | Group: Data collection / カテゴリ: chem_comp_atom / chem_comp_bond |
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Remark 650 | HELIX DETERMINATION METHOD: AUTHOR DETERMINED |
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Remark 700 | SHEET DETERMINATION METHOD: AUTHOR DETERMINED |
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