登録情報 データベース : PDB / ID : 2kec 構造の表示 ダウンロードとリンクタイトル Structure of SDF-1/CXCL12 要素Stromal cell-derived factor 1-alpha 詳細 キーワード CYTOKINE / stromal cell derived factor-1 / SDF1-alpha / CXCL12 / chemokine / Alternative splicing / Chemotaxis / Growth factor / Secreted機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
chemokine (C-X-C motif) ligand 12 signaling pathway / negative regulation of leukocyte tethering or rolling / response to ultrasound / telencephalon cell migration / regulation of actin polymerization or depolymerization / CXCL12-activated CXCR4 signaling pathway / chemokine receptor binding / positive regulation of vasculature development / CXCR chemokine receptor binding / positive regulation of axon extension involved in axon guidance ... chemokine (C-X-C motif) ligand 12 signaling pathway / negative regulation of leukocyte tethering or rolling / response to ultrasound / telencephalon cell migration / regulation of actin polymerization or depolymerization / CXCL12-activated CXCR4 signaling pathway / chemokine receptor binding / positive regulation of vasculature development / CXCR chemokine receptor binding / positive regulation of axon extension involved in axon guidance / positive regulation of dopamine secretion / Signaling by ROBO receptors / induction of positive chemotaxis / integrin activation / negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage / negative regulation of dendritic cell apoptotic process / cellular response to chemokine / chemokine-mediated signaling pathway / positive regulation of monocyte chemotaxis / blood circulation / Chemokine receptors bind chemokines / chemokine activity / positive regulation of calcium ion import / detection of temperature stimulus involved in sensory perception of pain / positive regulation of cell adhesion / positive regulation of T cell migration / animal organ regeneration / detection of mechanical stimulus involved in sensory perception of pain / Nuclear signaling by ERBB4 / positive regulation of endothelial cell proliferation / positive regulation of neuron differentiation / adult locomotory behavior / cell chemotaxis / axon guidance / growth factor activity / neuron migration / response to virus / response to peptide hormone / defense response / intracellular calcium ion homeostasis / chemotaxis / integrin binding / G alpha (i) signalling events / collagen-containing extracellular matrix / Estrogen-dependent gene expression / cell adhesion / response to hypoxia / immune response / G protein-coupled receptor signaling pathway / external side of plasma membrane / signaling receptor binding / signal transduction / extracellular exosome / extracellular region 類似検索 - 分子機能 CXC Chemokine domain / Chemokine beta/gamma/delta / Intercrine alpha family (small cytokine C-X-C) (chemokine CXC). / Chemokine interleukin-8-like domain / Chemokine interleukin-8-like superfamily / Small cytokines (intecrine/chemokine), interleukin-8 like / OB fold (Dihydrolipoamide Acetyltransferase, E2P) - #40 / OB fold (Dihydrolipoamide Acetyltransferase, E2P) / Beta Barrel / Mainly Beta 類似検索 - ドメイン・相同性生物種 Homo sapiens (ヒト)手法 溶液NMR / molecular dynamics 詳細Model details lowest energy, model 1 データ登録者 Volkman, B.F. / Veldkamp, C.T. / Peterson, F.C. 引用ジャーナル : Protein Sci. / 年 : 2009タイトル : Monomeric structure of the cardioprotective chemokine SDF-1/CXCL12著者 : Veldkamp, C.T. / Ziarek, J.J. / Su, J. / Basnet, H. / Lennertz, R. / Weiner, J.J. / Peterson, F.C. / Baker, J.E. / Volkman, B.F. 履歴 登録 2009年1月28日 登録サイト : BMRB / 処理サイト : RCSB改定 1.0 2009年9月29日 Provider : repository / タイプ : Initial release改定 1.1 2011年7月13日 Group : Version format compliance改定 1.2 2020年2月19日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other カテゴリ : pdbx_database_status / pdbx_nmr_software ... pdbx_database_status / pdbx_nmr_software / pdbx_nmr_spectrometer / pdbx_struct_assembly / pdbx_struct_oper_list / struct_ref_seq_dif Item : _pdbx_database_status.status_code_cs / _pdbx_nmr_software.name ... _pdbx_database_status.status_code_cs / _pdbx_nmr_software.name / _pdbx_nmr_spectrometer.model / _struct_ref_seq_dif.details 改定 1.3 2023年6月14日 Group : Database references / Other / カテゴリ : database_2 / pdbx_database_statusItem : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_nmr_data
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