Entry Database : PDB / ID : 2k6q Structure visualization Downloads & linksTitle LC3 p62 complex structure ComponentsMicrotubule-associated proteins 1A/1B light chain 3B p62_peptide from Sequestosome-1 DetailsKeywords APOPTOSIS INHIBITOR/APOPTOSIS / LC3 / p62 / Alternative splicing / Autophagy / Cytoplasm / Cytoplasmic vesicle / Lipoprotein / Membrane / Microtubule / Ubl conjugation pathway / Apoptosis / Differentiation / Endosome / Immune response / Metal-binding / Nucleus / Phosphoprotein / Zinc / Zinc-finger / APOPTOSIS INHIBITOR-APOPTOSIS COMPLEXFunction / homology Function and homology informationFunction Domain/homology Component
Receptor Mediated Mitophagy / Interleukin-1 signaling / TBC/RABGAPs / Pexophagy / NRIF signals cell death from the nucleus / NF-kB is activated and signals survival / p75NTR recruits signalling complexes / KEAP1-NFE2L2 pathway / PINK1-PRKN Mediated Mitophagy / positive regulation of mucus secretion ... Receptor Mediated Mitophagy / Interleukin-1 signaling / TBC/RABGAPs / Pexophagy / NRIF signals cell death from the nucleus / NF-kB is activated and signals survival / p75NTR recruits signalling complexes / KEAP1-NFE2L2 pathway / PINK1-PRKN Mediated Mitophagy / positive regulation of mucus secretion / brown fat cell proliferation / protein localization to perinuclear region of cytoplasm / Macroautophagy / protein targeting to vacuole involved in autophagy / Lewy body / response to mitochondrial depolarisation / ceramide binding / aggrephagy / amphisome / negative regulation of toll-like receptor 4 signaling pathway / mucus secretion / pexophagy / regulation of protein complex stability / endosome organization / non-membrane-bounded organelle assembly / molecular sequestering activity / phosphatidylethanolamine binding / ubiquitin-modified protein reader activity / phagophore assembly site / cellular response to nitrogen starvation / aggresome / regulation of canonical NF-kappaB signal transduction / negative regulation of ferroptosis / microtubule associated complex / autolysosome / intracellular non-membrane-bounded organelle / temperature homeostasis / immune system process / K63-linked polyubiquitin modification-dependent protein binding / axoneme / autophagosome membrane / autophagosome maturation / mitophagy / autophagosome assembly / autophagosome / endomembrane system / positive regulation of autophagy / signaling adaptor activity / energy homeostasis / inclusion body / sperm midpiece / negative regulation of protein ubiquitination / protein sequestering activity / ionotropic glutamate receptor binding / cellular response to starvation / sarcomere / positive regulation of protein localization to plasma membrane / tubulin binding / SH2 domain binding / molecular condensate scaffold activity / ubiquitin binding / positive regulation of long-term synaptic potentiation / response to ischemia / establishment of localization in cell / macroautophagy / protein kinase C binding / P-body / protein catabolic process / mitochondrial membrane / PML body / autophagy / protein import into nucleus / late endosome / presynapse / signaling receptor activity / protein-macromolecule adaptor activity / cytoplasmic vesicle / microtubule binding / microtubule / transcription by RNA polymerase II / cell differentiation / positive regulation of protein phosphorylation / protein domain specific binding / axon / neuronal cell body / ubiquitin protein ligase binding / glutamatergic synapse / synapse / dendrite / protein-containing complex binding / protein kinase binding / apoptotic process / enzyme binding / negative regulation of transcription by RNA polymerase II / endoplasmic reticulum / mitochondrion / zinc ion binding / identical protein binding / membrane / cytoplasm Similarity search - Function Sequestosome-1, UBA domain / Sequestosome-1, PB1 domain / : / UBA domain / PB1 domain / PB1 domain / PB1 domain profile. / PB1 domain / Autophagy protein Atg8 ubiquitin-like / Autophagy protein Atg8 ubiquitin like ... Sequestosome-1, UBA domain / Sequestosome-1, PB1 domain / : / UBA domain / PB1 domain / PB1 domain / PB1 domain profile. / PB1 domain / Autophagy protein Atg8 ubiquitin-like / Autophagy protein Atg8 ubiquitin like / Ubiquitin associated domain / Zinc finger ZZ-type signature. / Zinc-binding domain, present in Dystrophin, CREB-binding protein. / Zinc finger, ZZ type / Zinc finger, ZZ-type / Zinc finger, ZZ-type superfamily / Zinc finger ZZ-type profile. / Ubiquitin-associated domain / Ubiquitin-associated domain (UBA) profile. / UBA-like superfamily / Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 / Ubiquitin-like (UB roll) / Ubiquitin-like domain superfamily / Roll / Alpha Beta Similarity search - Domain/homologyBiological species Rattus norvegicus (Norway rat)Method SOLUTION NMR / simulated annealing , torsion angle dynamics DetailsAuthors Noda, N. / Kumeta, H. / Nakatogawa, H. / Satoo, K. / Adachi, W. / Ishii, J. / Fujioka, Y. / Ohsumi, Y. / Inagaki, F. CitationJournal : To be Published Title : Structural basis of target recognition by ATG8/LC3 during selective autophagyAuthors : Noda, N. / Kumeta, H. / Nakatogawa, H. / Adachi, K. / Adachi, W. / Ishii, J. / Fujioka, Y. / Ohsumi, Y. / Inagaki, F. History Deposition Jul 17, 2008 Deposition site : BMRB / Processing site : PDBJRevision 1.0 Sep 2, 2008 Provider : repository / Type : Initial releaseRevision 1.1 Jul 13, 2011 Group : Version format complianceRevision 1.2 Feb 26, 2020 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other Category : pdbx_database_status / pdbx_nmr_software ... pdbx_database_status / pdbx_nmr_software / pdbx_struct_assembly / pdbx_struct_oper_list / struct_ref_seq_dif Item : _pdbx_database_status.status_code_cs / _pdbx_nmr_software.name / _struct_ref_seq_dif.detailsRevision 1.3 Jun 14, 2023 Group : Database references / Other / Category : database_2 / pdbx_database_statusItem : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_nmr_dataRevision 1.4 May 15, 2024 Group : Data collection / Database references / Category : chem_comp_atom / chem_comp_bond / database_2 / Item : _database_2.pdbx_DOI
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