登録情報 | データベース: PDB / ID: 2fbs |
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タイトル | Solution structure of the LL-37 core peptide bound to detergent micelles |
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要素 | Antibacterial protein FALL-39, core peptide |
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キーワード | ANTIMICROBIAL PROTEIN / AMPHIPATHIC HELIX / LL-37 / host defense peptide / antimicrobial peptide |
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機能・相同性 | 機能・相同性情報
cytolysis / killing by host of symbiont cells / neutrophil activation / specific granule / cellular response to peptidoglycan / cellular response to interleukin-6 / Antimicrobial peptides / cellular response to interleukin-1 / innate immune response in mucosa / cell projection ...cytolysis / killing by host of symbiont cells / neutrophil activation / specific granule / cellular response to peptidoglycan / cellular response to interleukin-6 / Antimicrobial peptides / cellular response to interleukin-1 / innate immune response in mucosa / cell projection / lipopolysaccharide binding / specific granule lumen / positive regulation of angiogenesis / antimicrobial humoral immune response mediated by antimicrobial peptide / tertiary granule lumen / cellular response to tumor necrosis factor / antibacterial humoral response / cellular response to lipopolysaccharide / defense response to Gram-negative bacterium / amyloid fibril formation / defense response to Gram-positive bacterium / defense response to bacterium / positive regulation of protein phosphorylation / innate immune response / positive regulation of cell population proliferation / Neutrophil degranulation / extracellular space / extracellular exosome / extracellular region類似検索 - 分子機能 Cathelicidin, antimicrobial peptide, C-terminal / LPS binding domain of CAP18 (C terminal) / Cathelicidin / Cathelicidins signature 1. / Cathelicidin, conserved site / Cathelicidins signature 2. / Cathelicidin-like / Cystatin superfamily類似検索 - ドメイン・相同性 |
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手法 | 溶液NMR / simulated annealing |
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データ登録者 | Wang, G. / Li, X. |
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引用 | ジャーナル: J.Am.Chem.Soc. / 年: 2006 タイトル: Solution Structures of Human LL-37 Fragments and NMR-Based Identification of a Minimal Membrane-Targeting Antimicrobial and Anticancer Region 著者: Li, X. / Li, Y. / Han, H. / Miller, D.W. / Wang, G. |
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履歴 | 登録 | 2005年12月10日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2006年5月23日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年5月1日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2022年3月9日 | Group: Database references / Derived calculations カテゴリ: database_2 / pdbx_struct_assembly ...database_2 / pdbx_struct_assembly / pdbx_struct_oper_list / struct_conn / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_leaving_atom_flag / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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