- PDB-2ean: Solution structure of the N-terminal SAM-domain of human KIAA0902... -
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Basic information
Entry
Database: PDB / ID: 2ean
Title
Solution structure of the N-terminal SAM-domain of human KIAA0902 protein (connector enhancer of kinase suppressor of ras 2)
Components
Connector enhancer of kinase suppressor of ras 2
Keywords
SIGNALING PROTEIN / Cell-free protein synthesis / Protein regulation / Structural Genomics / NPPSFA / National Project on Protein Structural and Functional Analyses / RIKEN Structural Genomics/Proteomics Initiative / RSGI
Function / homology
Function and homology information
extrinsic component of postsynaptic density membrane / postsynapse organization / regulation of signal transduction / Signaling by high-kinase activity BRAF mutants / MAP2K and MAPK activation / Signaling by RAF1 mutants / Signaling by moderate kinase activity BRAF mutants / Paradoxical activation of RAF signaling by kinase inactive BRAF / Signaling downstream of RAS mutants / Signaling by BRAF and RAF1 fusions ...extrinsic component of postsynaptic density membrane / postsynapse organization / regulation of signal transduction / Signaling by high-kinase activity BRAF mutants / MAP2K and MAPK activation / Signaling by RAF1 mutants / Signaling by moderate kinase activity BRAF mutants / Paradoxical activation of RAF signaling by kinase inactive BRAF / Signaling downstream of RAS mutants / Signaling by BRAF and RAF1 fusions / intracellular signal transduction / neuronal cell body / glutamatergic synapse / protein kinase binding / extracellular exosome / identical protein binding / plasma membrane / cytoplasm Similarity search - Function
Connector enhancer of kinase suppressor of ras 2/3 domain / Connector enhancer of kinase suppressor of ras 2/3 domain / : / CRIC domain / Connector enhancer of kinase suppressor of ras / CRIC domain profile. / Transcription Factor, Ets-1 / SAM domain (Sterile alpha motif) / SAM domain profile. / Sterile alpha motif. ...Connector enhancer of kinase suppressor of ras 2/3 domain / Connector enhancer of kinase suppressor of ras 2/3 domain / : / CRIC domain / Connector enhancer of kinase suppressor of ras / CRIC domain profile. / Transcription Factor, Ets-1 / SAM domain (Sterile alpha motif) / SAM domain profile. / Sterile alpha motif. / Sterile alpha motif domain / PH domain / Sterile alpha motif/pointed domain superfamily / PH domain profile. / PDZ domain / Pleckstrin homology domain. / Pleckstrin homology domain / PDZ domain profile. / Domain present in PSD-95, Dlg, and ZO-1/2. / PDZ domain / PDZ superfamily / DNA polymerase; domain 1 / PH-like domain superfamily / Orthogonal Bundle / Mainly Alpha Similarity search - Domain/homology
Conformer selection criteria: structures with the least restraint violations Conformers calculated total number: 100 / Conformers submitted total number: 20
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