- PDB-2cr7: Solution structure of the first PAH domain of the mouse transcrip... -
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Basic information
Entry
Database: PDB / ID: 2cr7
Title
Solution structure of the first PAH domain of the mouse transcriptional repressor SIN3B
Components
Paired amphipathic helix protein Sin3b
Keywords
GENE REGULATION / Paired amphipathic helix repeat / Transcriptional repressor / Structural Genomics / NPPSFA / National Project on Protein Structural and Functional Analyses / RIKEN Structural Genomics/Proteomics Initiative / RSGI
Function / homology
Function and homology information
autosome / RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function / Regulation of lipid metabolism by PPARalpha / Cytoprotection by HMOX1 / XY body / cardiac muscle tissue development / Y chromosome / X chromosome / histone deacetylase complex / negative regulation of cell cycle ...autosome / RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function / Regulation of lipid metabolism by PPARalpha / Cytoprotection by HMOX1 / XY body / cardiac muscle tissue development / Y chromosome / X chromosome / histone deacetylase complex / negative regulation of cell cycle / skeletal muscle tissue development / negative regulation of cell migration / transcription corepressor activity / negative regulation of DNA-templated transcription / chromatin binding / chromatin / negative regulation of transcription by RNA polymerase II / nucleus / cytoplasm Similarity search - Function
Conformer selection criteria: target function, structures with the least restraint violations Conformers calculated total number: 100 / Conformers submitted total number: 20
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