登録情報 | データベース: PDB / ID: 2cqh |
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タイトル | Solution structure of the RNA binding domain of IGF-II mRNA-binding protein 2 |
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要素 | IGF-II mRNA-binding protein 2 isoform a |
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キーワード | RNA BINDING PROTEIN / RNA recognition motif / RRM / RNA binding domain / RBD / RNP / Structural Genomics / NPPSFA / National Project on Protein Structural and Functional Analyses / RIKEN Structural Genomics/Proteomics Initiative / RSGI |
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機能・相同性 | 機能・相同性情報
translation regulator activity, nucleic acid binding / cold-induced thermogenesis / Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA / CRD-mediated mRNA stabilization / N6-methyladenosine-containing RNA reader activity / mRNA transport / anatomical structure morphogenesis / translation regulator activity / energy homeostasis / regulation of cytokine production ...translation regulator activity, nucleic acid binding / cold-induced thermogenesis / Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA / CRD-mediated mRNA stabilization / N6-methyladenosine-containing RNA reader activity / mRNA transport / anatomical structure morphogenesis / translation regulator activity / energy homeostasis / regulation of cytokine production / mRNA 3'-UTR binding / P-body / mRNA 5'-UTR binding / cytoplasmic stress granule / nervous system development / regulation of gene expression / cytoskeleton / negative regulation of translation / RNA binding / nucleus / cytoplasm / cytosol類似検索 - 分子機能 IGF2BP2, RNA recognition motif 1 / KH domain / K Homology domain, type 1 / Type-1 KH domain profile. / K Homology domain, type 1 superfamily / RRM (RNA recognition motif) domain / RNA recognition motif / RNA recognition motif / Eukaryotic RNA Recognition Motif (RRM) profile. / RNA recognition motif domain ...IGF2BP2, RNA recognition motif 1 / KH domain / K Homology domain, type 1 / Type-1 KH domain profile. / K Homology domain, type 1 superfamily / RRM (RNA recognition motif) domain / RNA recognition motif / RNA recognition motif / Eukaryotic RNA Recognition Motif (RRM) profile. / RNA recognition motif domain / RNA-binding domain superfamily / K Homology domain / K homology RNA-binding domain / Nucleotide-binding alpha-beta plait domain superfamily / Alpha-Beta Plaits / 2-Layer Sandwich / Alpha Beta類似検索 - ドメイン・相同性 Insulin-like growth factor 2 mRNA-binding protein 2類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | 溶液NMR / torsion angle dyanamics, simulated annealing |
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データ登録者 | Suzuki, S. / Muto, Y. / Inoue, M. / Kigawa, T. / Terada, T. / Shirouzu, M. / Yokoyama, S. / RIKEN Structural Genomics/Proteomics Initiative (RSGI) |
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引用 | ジャーナル: To be Published タイトル: Solution structure of the RNA binding domain of IGF-II mRNA-binding protein 2 著者: Suzuki, S. / Muto, Y. / Inoue, M. / Kigawa, T. / Terada, T. / Shirouzu, M. / Yokoyama, S. |
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履歴 | 登録 | 2005年5月20日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
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改定 1.0 | 2005年11月20日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年4月30日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2022年3月9日 | Group: Data collection / Database references / Derived calculations カテゴリ: database_2 / pdbx_nmr_software ...database_2 / pdbx_nmr_software / pdbx_nmr_spectrometer / pdbx_struct_assembly / pdbx_struct_oper_list / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_nmr_software.name / _pdbx_nmr_spectrometer.model / _struct_ref_seq_dif.details |
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改定 1.4 | 2024年5月29日 | Group: Data collection / カテゴリ: chem_comp_atom / chem_comp_bond |
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Remark 650 | HELIX DETERMINATION METHOD: AUTHOR DETERMINED |
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Remark 700 | SHEET DETERMINATION METHOD: AUTHOR DETERMINED |
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