+Open data
-Basic information
Entry | Database: PDB / ID: 2bfo | ||||||
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Title | Leishmania major pteridine reductase 1 in complex with NADPH | ||||||
Components | PTERIDINE REDUCTASE 1 | ||||||
Keywords | OXIDOREDUCTASE / PTERIDINE REDUCTASE / TRYPANOSOMATIDS / DRUG RESISTANCE / PTERIN SALVAGE / SHORT-CHAIN DEHYDROGENASE/REDUCTASE / METHOTREXATE RESISTANCE / NADP | ||||||
Function / homology | Function and homology information pteridine reductase / 6,7-dihydropteridine reductase activity / pteridine reductase activity / tetrahydrobiopterin biosynthetic process / response to methotrexate / oxidoreductase activity / cytosol Similarity search - Function | ||||||
Biological species | LEISHMANIA MAJOR (eukaryote) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.6 Å | ||||||
Authors | Schuettelkopf, A.W. / Hunter, W.N. | ||||||
Citation | Journal: J.Mol.Biol. / Year: 2005 Title: Structures of Leishmania Major Pteridine Reductase Complexes Reveal the Active Site Features Important for Ligand Binding and to Guide Inhibitor Design Authors: Schuettelkopf, A.W. / Hardy, L.W. / Beverley, S.M. / Hunter, W.N. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 2bfo.cif.gz | 215.7 KB | Display | PDBx/mmCIF format |
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PDB format | pdb2bfo.ent.gz | 173.8 KB | Display | PDB format |
PDBx/mmJSON format | 2bfo.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/bf/2bfo ftp://data.pdbj.org/pub/pdb/validation_reports/bf/2bfo | HTTPS FTP |
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-Related structure data
Related structure data | 2bf7C 2bfaC 2bfmC 2bfpC 1e92S C: citing same article (ref.) S: Starting model for refinement |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Refine code: 1
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