Entry Database : PDB / ID : 1zok Structure visualization Downloads & linksTitle PDZ1 Domain Of Synapse Associated Protein 97 ComponentsPresynaptic protein SAP97 Details Keywords MEMBRANE PROTEIN / PDZ / PDZ1 / SAP97 / Synapse Associated Protein 97 / Beta Strand / HelixFunction / homology Function and homology informationFunction Domain/homology Component
tissue morphogenesis / regulation of protein localization to synapse / regulation of potassium ion import / L27 domain binding / regulation of potassium ion export across plasma membrane / MPP7-DLG1-LIN7 complex / membrane raft organization / hard palate development / establishment of centrosome localization / negative regulation of p38MAPK cascade ... tissue morphogenesis / regulation of protein localization to synapse / regulation of potassium ion import / L27 domain binding / regulation of potassium ion export across plasma membrane / MPP7-DLG1-LIN7 complex / membrane raft organization / hard palate development / establishment of centrosome localization / negative regulation of p38MAPK cascade / cortical microtubule organization / embryonic skeletal system morphogenesis / astral microtubule organization / structural constituent of postsynaptic density / lateral loop / reproductive structure development / immunological synapse formation / myelin sheath abaxonal region / peristalsis / cell projection membrane / smooth muscle tissue development / paranode region of axon / bicellular tight junction assembly / positive regulation of potassium ion transport / Trafficking of AMPA receptors / Activation of Ca-permeable Kainate Receptor / node of Ranvier / regulation of ventricular cardiac muscle cell action potential / protein-containing complex localization / establishment or maintenance of epithelial cell apical/basal polarity / amyloid precursor protein metabolic process / Synaptic adhesion-like molecules / RAF/MAP kinase cascade / neurotransmitter receptor localization to postsynaptic specialization membrane / endothelial cell proliferation / lens development in camera-type eye / regulation of myelination / ureteric bud development / cortical actin cytoskeleton organization / branching involved in ureteric bud morphogenesis / negative regulation of G1/S transition of mitotic cell cycle / positive regulation of actin filament polymerization / receptor clustering / kinesin binding / microvillus / immunological synapse / basement membrane / lateral plasma membrane / potassium channel regulator activity / bicellular tight junction / Unblocking of NMDA receptors, glutamate binding and activation / postsynaptic density, intracellular component / phosphatase binding / negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction / T cell proliferation / negative regulation of T cell proliferation / cellular response to brain-derived neurotrophic factor stimulus / T-tubule / T cell activation / actin filament polymerization / phosphatidylinositol 3-kinase/protein kinase B signal transduction / basal plasma membrane / synaptic membrane / protein localization to plasma membrane / PDZ domain binding / regulation of membrane potential / positive regulation of protein localization to plasma membrane / actin filament organization / postsynaptic density membrane / ionotropic glutamate receptor binding / neuromuscular junction / protein localization / cytoplasmic side of plasma membrane / negative regulation of ERK1 and ERK2 cascade / cerebral cortex development / synaptic vesicle membrane / cell-cell adhesion / negative regulation of epithelial cell proliferation / regulation of protein localization / cell-cell junction / cell junction / presynaptic membrane / regulation of cell shape / chemical synaptic transmission / basolateral plasma membrane / postsynaptic membrane / microtubule / transmembrane transporter binding / cell population proliferation / molecular adaptor activity / postsynaptic density / cell adhesion / neuron projection / membrane raft / apical plasma membrane / neuronal cell body / glutamatergic synapse / synapse / dendrite / positive regulation of cell population proliferation Similarity search - Function L27-1 / L27_1 / domain in receptor targeting proteins Lin-2 and Lin-7 / L27 domain / L27 domain profile. / L27 domain superfamily / Polyubiquitination (PEST) N-terminal domain of MAGUK / Disks large homologue 1, N-terminal PEST domain / Polyubiquitination (PEST) N-terminal domain of MAGUK / PDZ-associated domain of NMDA receptors ... L27-1 / L27_1 / domain in receptor targeting proteins Lin-2 and Lin-7 / L27 domain / L27 domain profile. / L27 domain superfamily / Polyubiquitination (PEST) N-terminal domain of MAGUK / Disks large homologue 1, N-terminal PEST domain / Polyubiquitination (PEST) N-terminal domain of MAGUK / PDZ-associated domain of NMDA receptors / PDZ-associated domain of NMDA receptors / Disks large 1-like / Guanylate kinase, conserved site / Guanylate kinase-like signature. / Guanylate kinase-like domain profile. / Guanylate kinase-like domain / Guanylate kinase/L-type calcium channel beta subunit / Guanylate kinase / Guanylate kinase homologues. / PDZ domain / Pdz3 Domain / PDZ domain / SH3 domain / PDZ domain profile. / Domain present in PSD-95, Dlg, and ZO-1/2. / PDZ domain / PDZ superfamily / Src homology 3 domains / SH3-like domain superfamily / Src homology 3 (SH3) domain profile. / SH3 domain / Roll / P-loop containing nucleoside triphosphate hydrolase / Mainly Beta Similarity search - Domain/homologyBiological species Rattus norvegicus (Norway rat)Method SOLUTION NMR / torsion angle dynamics DetailsAuthors Wang, L. / Piserchio, A. / Mierke, D.F. CitationJournal : J.Biol.Chem. / Year : 2005Title : Structural Characterization of the Intermolecular Interactions of Synapse-associated Protein-97 with the NR2B Subunit of N-Methyl-D-aspartate Receptors.Authors : Wang, L. / Piserchio, A. / Mierke, D.F. History Deposition May 13, 2005 Deposition site : RCSB / Processing site : RCSBRevision 1.0 Jun 7, 2005 Provider : repository / Type : Initial releaseRevision 1.1 Apr 30, 2008 Group : Version format complianceRevision 1.2 Jul 13, 2011 Group : Version format complianceRevision 1.3 Mar 2, 2022 Group : Data collection / Database references / Derived calculationsCategory : database_2 / pdbx_nmr_software ... database_2 / pdbx_nmr_software / pdbx_nmr_spectrometer / pdbx_struct_assembly / pdbx_struct_oper_list Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_nmr_software.name / _pdbx_nmr_spectrometer.model Revision 1.4 May 22, 2024 Group : Data collection / Category : chem_comp_atom / chem_comp_bond
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