[English] 日本語
Yorodumi- PDB-1zjp: Crystal Structure of Human Galactosyltransferase (GTB) Complexed ... -
+Open data
-Basic information
Entry | Database: PDB / ID: 1zjp | ||||||
---|---|---|---|---|---|---|---|
Title | Crystal Structure of Human Galactosyltransferase (GTB) Complexed with Galactose-grease | ||||||
Components | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) | ||||||
Keywords | TRANSFERASE / GTB / ABO(H) / blood group / H-antigen / glycosyltransferase / retaining | ||||||
Function / homology | Function and homology information fucosylgalactoside 3-alpha-galactosyltransferase / glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase / glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity / fucosylgalactoside 3-alpha-galactosyltransferase activity / ABO blood group biosynthesis / lipid glycosylation / Golgi cisterna membrane / protein glycosylation / antigen binding / manganese ion binding ...fucosylgalactoside 3-alpha-galactosyltransferase / glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase / glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity / fucosylgalactoside 3-alpha-galactosyltransferase activity / ABO blood group biosynthesis / lipid glycosylation / Golgi cisterna membrane / protein glycosylation / antigen binding / manganese ion binding / vesicle / carbohydrate metabolic process / Golgi membrane / nucleotide binding / Golgi apparatus / extracellular region Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | X-RAY DIFFRACTION / MOLECULAR REPLACEMENT / Resolution: 1.59 Å | ||||||
Authors | Letts, J.A. / Rose, N.L. / Fang, Y.R. / Barry, C.H. / Borisova, S.N. / Seto, N.O. / Palcic, M.M. / Evans, S.V. | ||||||
Citation | Journal: J.Biol.Chem. / Year: 2006 Title: Differential Recognition of the Type I and II H Antigen Acceptors by the Human ABO(H) Blood Group A and B Glycosyltransferases. Authors: Letts, J.A. / Rose, N.L. / Fang, Y.R. / Barry, C.H. / Borisova, S.N. / Seto, N.O. / Palcic, M.M. / Evans, S.V. | ||||||
History |
|
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
---|
-Downloads & links
-Download
PDBx/mmCIF format | 1zjp.cif.gz | 75.9 KB | Display | PDBx/mmCIF format |
---|---|---|---|---|
PDB format | pdb1zjp.ent.gz | 54 KB | Display | PDB format |
PDBx/mmJSON format | 1zjp.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/zj/1zjp ftp://data.pdbj.org/pub/pdb/validation_reports/zj/1zjp | HTTPS FTP |
---|
-Related structure data
Related structure data | 1zhjC 1zi1C 1zi3C 1zi4C 1zi5C 1zizC 1zj0C 1zj1C 1zj2C 1zj3C 1zjoC 2a8uC 2a8wC 1lz7S C: citing same article (ref.) S: Starting model for refinement |
---|---|
Similar structure data |
-Links
-Assembly
Deposited unit |
| ||||||||
---|---|---|---|---|---|---|---|---|---|
1 |
| ||||||||
2 |
| ||||||||
Unit cell |
| ||||||||
Components on special symmetry positions |
|
-Components
-Protein / Sugars , 2 types, 2 molecules A
#1: Protein | Mass: 34156.445 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Homo sapiens (human) / Plasmid: PCW DELTA 1AC (E-H) / Production host: Escherichia coli (E. coli) / Strain (production host): BL21Gold / References: UniProt: P16442 |
---|---|
#5: Sugar | ChemComp-DR4 / |
-Non-polymers , 5 types, 203 molecules
#2: Chemical | ChemComp-HG / #3: Chemical | ChemComp-CL / | #4: Chemical | ChemComp-MN / | #6: Chemical | ChemComp-UDP / | #7: Water | ChemComp-HOH / | |
---|
-Experimental details
-Experiment
Experiment | Method: X-RAY DIFFRACTION |
---|
-Sample preparation
Crystal | Density Matthews: 2.28 Å3/Da / Density % sol: 46.03 % |
---|
-Data collection
Diffraction | Mean temperature: 113 K |
---|---|
Detector | Type: RIGAKU RAXIS IV / Detector: IMAGE PLATE / Date: Apr 18, 2005 |
Radiation | Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Relative weight: 1 |
-Processing
Software |
| ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Refinement | Method to determine structure: MOLECULAR REPLACEMENT Starting model: 1LZ7 Resolution: 1.59→20 Å /
| ||||||||||||||||||
Refinement step | Cycle: LAST / Resolution: 1.59→20 Å
|