登録情報 | データベース: PDB / ID: 1zgw |
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タイトル | NMR structure of E. Coli Ada protein in complex with DNA |
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要素 | - 5'-D(*GP*CP*AP*AP*AP*TP*TP*AP*AP*AP*GP*CP*GP*CP*AP*AP*GP*A)-3'
- 5'-D(*TP*CP*TP*TP*GP*CP*GP*CP*TP*TP*TP*AP*AP*TP*TP*TP*GP*C)-3'
- Ada polyprotein
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キーワード | TRANSCRIPTION REGULATOR/DNA / Protein-DNA complex / helix-turn-helix / Zinc ligand / TRANSCRIPTION REGULATOR-DNA COMPLEX |
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機能・相同性 | 機能・相同性情報
: / methylated-DNA-[protein]-cysteine S-methyltransferase / methylated-DNA-[protein]-cysteine S-methyltransferase activity / : / DNA alkylation repair / sequence-specific DNA binding / methylation / DNA-binding transcription factor activity / negative regulation of DNA-templated transcription / DNA damage response ...: / methylated-DNA-[protein]-cysteine S-methyltransferase / methylated-DNA-[protein]-cysteine S-methyltransferase activity / : / DNA alkylation repair / sequence-specific DNA binding / methylation / DNA-binding transcription factor activity / negative regulation of DNA-templated transcription / DNA damage response / positive regulation of DNA-templated transcription / zinc ion binding類似検索 - 分子機能 DNA Methylphosphotriester Repair Domain / DNA Methylphosphotriester Repair Domain / Ada DNA repair, metal-binding / Bifunctional regulatory protein Ada / Ada-like domain superfamily / Metal binding domain of Ada / Bacterial regulatory helix-turn-helix proteins, AraC family / Methylguanine DNA methyltransferase, ribonuclease-like domain / 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain / Methylated DNA-protein cysteine methyltransferase domain superfamily ...DNA Methylphosphotriester Repair Domain / DNA Methylphosphotriester Repair Domain / Ada DNA repair, metal-binding / Bifunctional regulatory protein Ada / Ada-like domain superfamily / Metal binding domain of Ada / Bacterial regulatory helix-turn-helix proteins, AraC family / Methylguanine DNA methyltransferase, ribonuclease-like domain / 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain / Methylated DNA-protein cysteine methyltransferase domain superfamily / Methylated-DNA-[protein]-cysteine S-methyltransferase, active site / Methylated-DNA--protein-cysteine methyltransferase active site. / HTH domain AraC-type, conserved site / Bacterial regulatory proteins, araC family signature. / Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding / Methylated DNA-protein cysteine methyltransferase, DNA binding domain / 6-O-methylguanine DNA methyltransferase, DNA binding domain / DNA binding HTH domain, AraC-type / Helix-turn-helix domain / Bacterial regulatory proteins, araC family DNA-binding domain profile. / helix_turn_helix, arabinose operon control protein / Homeodomain-like / Homeobox-like domain superfamily / Arc Repressor Mutant, subunit A / Winged helix-like DNA-binding domain superfamily / Orthogonal Bundle / 3-Layer(aba) Sandwich / Mainly Alpha / Alpha Beta類似検索 - ドメイン・相同性 DNA / DNA (> 10) / Bifunctional transcriptional activator/DNA repair enzyme Ada類似検索 - 構成要素 |
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生物種 | ![](img/tx_bacteria.gif) Escherichia coli (大腸菌) |
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手法 | 溶液NMR / simulated annealing |
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データ登録者 | He, C. / Hus, J.C. / Sun, L.J. / Zhou, P. / Norman, D.P. / Doetsch, V. / Wei, H. / Gross, J.D. / Lane, W.S. / Wagner, G. / Verdine, G.L. |
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引用 | ジャーナル: Mol.Cell / 年: 2005 タイトル: A Methylation-Dependent Electrostatic Switch Controls DNA Repair and Transcriptional Activation by E. coli Ada. 著者: He, C. / Hus, J.C. / Sun, L.J. / Zhou, P. / Norman, D.P. / Doetsch, V. / Wei, H. / Gross, J.D. / Lane, W.S. / Wagner, G. / Verdine, G.L. |
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履歴 | 登録 | 2005年4月22日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2005年10月18日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年4月30日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2022年3月2日 | Group: Data collection / Database references / Derived calculations カテゴリ: database_2 / pdbx_nmr_software ...database_2 / pdbx_nmr_software / pdbx_nmr_spectrometer / pdbx_struct_assembly / pdbx_struct_oper_list / struct_conn / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_nmr_software.name / _pdbx_nmr_spectrometer.model / _struct_conn.pdbx_leaving_atom_flag / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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