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- PDB-1ytz: Crystal structure of skeletal muscle troponin in the Ca2+-activat... -
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Open data
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Basic information
Entry | Database: PDB / ID: 1ytz | ||||||
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Title | Crystal structure of skeletal muscle troponin in the Ca2+-activated state | ||||||
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![]() | CONTRACTILE PROTEIN / troponin / muscle / thin filament / actin binding / calcium | ||||||
Function / homology | ![]() troponin C binding / troponin complex / Striated Muscle Contraction / regulation of muscle contraction / myosin II complex / sarcomere organization / tropomyosin binding / troponin I binding / skeletal muscle contraction / cardiac muscle contraction ...troponin C binding / troponin complex / Striated Muscle Contraction / regulation of muscle contraction / myosin II complex / sarcomere organization / tropomyosin binding / troponin I binding / skeletal muscle contraction / cardiac muscle contraction / actin binding / calcium ion binding Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Vinogradova, M.V. / Stone, D.B. / Malanina, G.G. / Karatzaferi, C. / Cooke, R. / Mendelson, R.A. / Fletterick, R.J. | ||||||
![]() | ![]() Title: Ca2+-regulated structural changes in troponin Authors: Vinogradova, M.V. / Stone, D.B. / Malanina, G.G. / Karatzaferi, C. / Cooke, R. / Mendelson, R.A. / Fletterick, R.J. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 101.5 KB | Display | ![]() |
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PDB format | ![]() | 73.3 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 937.6 KB | Display | ![]() |
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Full document | ![]() | 962.5 KB | Display | |
Data in XML | ![]() | 20.1 KB | Display | |
Data in CIF | ![]() | 26.1 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
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Links
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Assembly
Deposited unit | ![]()
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2 | ![]()
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Unit cell |
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Components
-Protein , 3 types, 3 molecules TIC
#1: Protein | Mass: 12694.692 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() |
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#2: Protein | Mass: 21116.246 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() |
#3: Protein | Mass: 18261.188 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() |
-Non-polymers , 3 types, 40 molecules ![](data/chem/img/DR6.gif)
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#4: Chemical | #5: Chemical | ChemComp-CA / #6: Water | ChemComp-HOH / | |
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-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 3.864 Å3/Da / Density % sol: 67 % |
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Crystal grow | Temperature: 298 K / Method: vapor diffusion, sitting drop / pH: 8 Details: 0.4 M NaH2PO4/1.6 M K2HPO4, 200 mM NaCl, 0.1 M immidazole, pH 8.0, VAPOR DIFFUSION, SITTING DROP, temperature 298K |
-Data collection
Diffraction | Mean temperature: 100 K |
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Diffraction source | Source: ![]() ![]() ![]() |
Detector | Type: ADSC QUANTUM 4 / Detector: CCD / Date: May 22, 2002 |
Radiation | Monochromator: double crystal / Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength: 1.1 Å / Relative weight: 1 |
Reflection | Resolution: 3→25 Å / Num. all: 16801 / Num. obs: 16095 / % possible obs: 95.9 % / Observed criterion σ(F): 0 / Observed criterion σ(I): 0 / Rmerge(I) obs: 0.055 |
Reflection shell | Resolution: 3→3.11 Å / % possible all: 90.8 |
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Processing
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Refinement | Method to determine structure: ![]()
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Refinement step | Cycle: LAST / Resolution: 3→25 Å
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Refine LS restraints |
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LS refinement shell |
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