登録情報 | データベース: PDB / ID: 1yk0 |
---|
タイトル | structure of natriuretic peptide receptor-C complexed with atrial natriuretic peptide |
---|
要素 | (Atrial natriuretic ...) x 2 |
---|
キーワード | HORMONE/GROWTH FACTOR RECEPTOR / HORMONE-RECEPTOR COMPLEX / NATRIURETIC PEPTIDE RECEPTOR / ALLOSTERIC ACTIVATION / HORMONE-GROWTH FACTOR RECEPTOR COMPLEX |
---|
機能・相同性 | 機能・相同性情報
positive regulation of delayed rectifier potassium channel activity / natriuretic peptide receptor activity / osteoclast proliferation / receptor guanylyl cyclase signaling pathway / neuropeptide receptor binding / regulation of high voltage-gated calcium channel activity / positive regulation of potassium ion export across plasma membrane / cGMP biosynthetic process / regulation of atrial cardiac muscle cell membrane repolarization / Physiological factors ...positive regulation of delayed rectifier potassium channel activity / natriuretic peptide receptor activity / osteoclast proliferation / receptor guanylyl cyclase signaling pathway / neuropeptide receptor binding / regulation of high voltage-gated calcium channel activity / positive regulation of potassium ion export across plasma membrane / cGMP biosynthetic process / regulation of atrial cardiac muscle cell membrane repolarization / Physiological factors / cardiac conduction system development / YAP1- and WWTR1 (TAZ)-stimulated gene expression / hormone binding / positive regulation of urine volume / negative regulation of JUN kinase activity / regulation of osteoblast proliferation / sodium ion export across plasma membrane / neuropeptide hormone activity / G protein-coupled peptide receptor activity / cardiac muscle hypertrophy in response to stress / negative regulation of systemic arterial blood pressure / hormone receptor binding / aortic valve morphogenesis / negative regulation of cold-induced thermogenesis / regulation of calcium ion transmembrane transport via high voltage-gated calcium channel / chloride ion binding / positive regulation of heart rate / cGMP-mediated signaling / peptide hormone binding / neuropeptide signaling pathway / blood vessel remodeling / positive regulation of cardiac muscle contraction / response to muscle stretch / positive regulation of nitric-oxide synthase activity / skeletal system development / cell projection / response to ischemia / female pregnancy / peptide binding / hormone activity / regulation of blood pressure / vasodilation / protein folding / perikaryon / angiogenesis / collagen-containing extracellular matrix / Amyloid fiber formation / signaling receptor binding / signal transduction / protein homodimerization activity / protein-containing complex / extracellular space / extracellular exosome / extracellular region / plasma membrane / cytoplasm類似検索 - 分子機能 Natriuretic peptide, atrial type / Adenylyl cyclase class-4/guanylyl cyclase / Natriuretic peptides receptors signature. / Natriuretic peptide, conserved site / Atrial natriuretic peptide / Natriuretic peptides signature. / Natriuretic peptide / Natriuretic peptide / Response regulator / Receptor, ligand binding region ...Natriuretic peptide, atrial type / Adenylyl cyclase class-4/guanylyl cyclase / Natriuretic peptides receptors signature. / Natriuretic peptide, conserved site / Atrial natriuretic peptide / Natriuretic peptides signature. / Natriuretic peptide / Natriuretic peptide / Response regulator / Receptor, ligand binding region / Receptor family ligand binding region / Periplasmic binding protein-like I / Rossmann fold / 3-Layer(aba) Sandwich / Alpha Beta類似検索 - ドメイン・相同性 Natriuretic peptides A / Atrial natriuretic peptide receptor 3類似検索 - 構成要素 |
---|
生物種 | Homo sapiens (ヒト) |
---|
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.4 Å |
---|
データ登録者 | He, X. / Garcia, K.C. |
---|
引用 | ジャーナル: J.Mol.Biol. / 年: 2006 タイトル: Structural determinants of natriuretic peptide receptor specificity and degeneracy. 著者: He, X.L. / Dukkipati, A. / Garcia, K.C. |
---|
履歴 | 登録 | 2005年1月16日 | 登録サイト: RCSB / 処理サイト: RCSB |
---|
改定 1.0 | 2006年4月18日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2008年4月30日 | Group: Version format compliance |
---|
改定 1.2 | 2011年7月13日 | Group: Non-polymer description / Version format compliance |
---|
改定 2.0 | 2020年7月29日 | Group: Advisory / Atomic model ...Advisory / Atomic model / Data collection / Derived calculations / Structure summary カテゴリ: atom_site / chem_comp ...atom_site / chem_comp / database_PDB_caveat / entity / pdbx_branch_scheme / pdbx_chem_comp_identifier / pdbx_entity_branch / pdbx_entity_branch_descriptor / pdbx_entity_branch_link / pdbx_entity_branch_list / pdbx_entity_nonpoly / pdbx_nonpoly_scheme / pdbx_struct_assembly_gen / struct_asym / struct_conn / struct_site / struct_site_gen Item: _atom_site.B_iso_or_equiv / _atom_site.Cartn_x ..._atom_site.B_iso_or_equiv / _atom_site.Cartn_x / _atom_site.Cartn_y / _atom_site.Cartn_z / _atom_site.auth_asym_id / _atom_site.auth_atom_id / _atom_site.auth_comp_id / _atom_site.auth_seq_id / _atom_site.label_asym_id / _atom_site.label_atom_id / _atom_site.label_comp_id / _atom_site.label_entity_id / _atom_site.type_symbol / _chem_comp.name / _chem_comp.type / _pdbx_entity_nonpoly.entity_id / _pdbx_entity_nonpoly.name / _pdbx_struct_assembly_gen.asym_id_list / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.pdbx_role / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id 解説: Carbohydrate remediation / Provider: repository / タイプ: Remediation |
---|
改定 2.1 | 2023年8月23日 | Group: Data collection / Database references ...Data collection / Database references / Refinement description / Structure summary カテゴリ: chem_comp / chem_comp_atom ...chem_comp / chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _chem_comp.pdbx_synonyms / _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
---|
|
---|