- PDB-1wsp: Crystal structure of axin dix domain -
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基本情報
登録情報
データベース: PDB / ID: 1wsp
タイトル
Crystal structure of axin dix domain
要素
Axin 1 protein
キーワード
SIGNALING PROTEIN
機能・相同性
機能・相同性情報
Beta-catenin phosphorylation cascade / Disassembly of the destruction complex and recruitment of AXIN to the membrane / TCF dependent signaling in response to WNT / Degradation of beta-catenin by the destruction complex / Degradation of AXIN / embryonic skeletal joint morphogenesis / armadillo repeat domain binding / response to quercetin / hemoglobin metabolic process / head development ...Beta-catenin phosphorylation cascade / Disassembly of the destruction complex and recruitment of AXIN to the membrane / TCF dependent signaling in response to WNT / Degradation of beta-catenin by the destruction complex / Degradation of AXIN / embryonic skeletal joint morphogenesis / armadillo repeat domain binding / response to quercetin / hemoglobin metabolic process / head development / cell development / Ub-specific processing proteases / dorsal/ventral axis specification / axial mesoderm formation / post-anal tail morphogenesis / axial mesoderm development / beta-catenin destruction complex / epigenetic programming in the zygotic pronuclei / positive regulation of ubiquitin-dependent protein catabolic process / dorsal/ventral pattern formation / I-SMAD binding / nervous system process / Wnt signalosome / adult walking behavior / regulation of canonical Wnt signaling pathway / negative regulation of protein metabolic process / nucleocytoplasmic transport / erythrocyte homeostasis / negative regulation of fat cell differentiation / negative regulation of Wnt signaling pathway / positive regulation of transforming growth factor beta receptor signaling pathway / negative regulation of transcription elongation by RNA polymerase II / SMAD binding / R-SMAD binding / ubiquitin-like ligase-substrate adaptor activity / lateral plasma membrane / canonical Wnt signaling pathway / cytoplasmic microtubule organization / positive regulation of peptidyl-threonine phosphorylation / positive regulation of protein ubiquitination / cell periphery / sensory perception of sound / positive regulation of JNK cascade / regulation of protein phosphorylation / negative regulation of canonical Wnt signaling pathway / protein catabolic process / Wnt signaling pathway / beta-catenin binding / protein polyubiquitination / positive regulation of protein catabolic process / microtubule cytoskeleton / p53 binding / positive regulation of proteasomal ubiquitin-dependent protein catabolic process / positive regulation of peptidyl-serine phosphorylation / cell cortex / cytoplasmic vesicle / protein-containing complex assembly / in utero embryonic development / molecular adaptor activity / positive regulation of protein phosphorylation / protein domain specific binding / negative regulation of gene expression / signaling receptor binding / ubiquitin protein ligase binding / synapse / apoptotic process / protein kinase binding / perinuclear region of cytoplasm / enzyme binding / protein homodimerization activity / protein-containing complex / identical protein binding / nucleus / plasma membrane / cytoplasm 類似検索 - 分子機能