登録情報 | データベース: PDB / ID: 1wdz |
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タイトル | Crystal structure of RCB domain of IRSp53 |
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要素 | insulin receptor substrate p53 |
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キーワード | SIGNALING PROTEIN / cellular signaling protein / RIKEN Structural Genomics/Proteomics Initiative / RSGI / Structural Genomics |
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機能・相同性 | 機能・相同性情報
neuron projection branch point / dendritic spine cytoplasm / plasma membrane organization / actin crosslink formation / positive regulation of dendritic spine morphogenesis / cellular response to L-glutamate / protein localization to synapse / cadherin binding involved in cell-cell adhesion / cytoskeletal anchor activity / regulation of modification of postsynaptic actin cytoskeleton ...neuron projection branch point / dendritic spine cytoplasm / plasma membrane organization / actin crosslink formation / positive regulation of dendritic spine morphogenesis / cellular response to L-glutamate / protein localization to synapse / cadherin binding involved in cell-cell adhesion / cytoskeletal anchor activity / regulation of modification of postsynaptic actin cytoskeleton / presynaptic cytosol / neuron projection terminus / proline-rich region binding / postsynaptic cytosol / positive regulation of actin filament polymerization / dendrite development / positive regulation of excitatory postsynaptic potential / CDC42 GTPase cycle / actin filament bundle assembly / excitatory synapse / RAC3 GTPase cycle / RHO GTPases Activate WASPs and WAVEs / postsynaptic density, intracellular component / cellular response to epidermal growth factor stimulus / ruffle / RAC1 GTPase cycle / axonogenesis / dendritic shaft / synaptic membrane / secretory granule / filopodium / transcription coregulator binding / PDZ domain binding / regulation of actin cytoskeleton organization / adherens junction / FCGR3A-mediated phagocytosis / Schaffer collateral - CA1 synapse / regulation of synaptic plasticity / Regulation of actin dynamics for phagocytic cup formation / VEGFA-VEGFR2 Pathway / insulin receptor signaling pathway / lamellipodium / regulation of cell shape / scaffold protein binding / microtubule / neuronal cell body / glutamatergic synapse / extracellular exosome / nucleoplasm / identical protein binding / plasma membrane / cytoplasm / cytosol類似検索 - 分子機能 I-BAR domain containing protein IRSp53 / IRSp53, SH3 domain / I-BAR domain containing protein IRSp53/IRTKS/Pinkbar / IMD/I-BAR domain / IRSp53/MIM homology domain / IMD domain profile. / Arfaptin homology (AH) domain/BAR domain / AH/BAR domain superfamily / Variant SH3 domain / Substrate Binding Domain Of Dnak; Chain:A; Domain 2 ...I-BAR domain containing protein IRSp53 / IRSp53, SH3 domain / I-BAR domain containing protein IRSp53/IRTKS/Pinkbar / IMD/I-BAR domain / IRSp53/MIM homology domain / IMD domain profile. / Arfaptin homology (AH) domain/BAR domain / AH/BAR domain superfamily / Variant SH3 domain / Substrate Binding Domain Of Dnak; Chain:A; Domain 2 / Src homology 3 domains / SH3-like domain superfamily / Src homology 3 (SH3) domain profile. / SH3 domain / Up-down Bundle / Mainly Alpha類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 単一同系置換・異常分散 / 解像度: 2.63 Å |
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データ登録者 | Murayama, K. / Suetsugu, S. / Seto, A. / Shirouzu, M. / Takenawa, T. / Yokoyama, S. / RIKEN Structural Genomics/Proteomics Initiative (RSGI) |
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引用 | ジャーナル: TO BE PUBLISHED タイトル: Crystal structure of RCB domain of IRSp53 著者: Murayama, K. / Suetsugu, S. / Seto, A. / Shirouzu, M. / Takenawa, T. / Yokoyama, S. |
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履歴 | 登録 | 2004年5月21日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
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改定 1.0 | 2005年6月7日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年4月30日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2024年3月13日 | Group: Data collection / Database references カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details |
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