+Open data
-Basic information
Entry | Database: PDB / ID: 1vnd | ||||||
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Title | VND/NK-2 PROTEIN (HOMEODOMAIN), NMR | ||||||
Components | VND/NK-2 PROTEIN | ||||||
Keywords | DNA BINDING PROTEIN / DNA-BINDING PROTEIN | ||||||
Function / homology | Function and homology information neuroblast development / neuroblast fate determination / glial cell development / brain development / DNA-binding transcription factor binding / cell differentiation / DNA-binding transcription factor activity, RNA polymerase II-specific / RNA polymerase II cis-regulatory region sequence-specific DNA binding / negative regulation of gene expression / regulation of transcription by RNA polymerase II ...neuroblast development / neuroblast fate determination / glial cell development / brain development / DNA-binding transcription factor binding / cell differentiation / DNA-binding transcription factor activity, RNA polymerase II-specific / RNA polymerase II cis-regulatory region sequence-specific DNA binding / negative regulation of gene expression / regulation of transcription by RNA polymerase II / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / nucleus Similarity search - Function | ||||||
Biological species | Drosophila melanogaster (fruit fly) | ||||||
Method | SOLUTION NMR | ||||||
Authors | Tsao, D.H.H. / Gruschus, J.M. / Wang, L.-H. / Nirenberg, M. / Ferretti, J.A. | ||||||
Citation | Journal: J.Mol.Biol. / Year: 1995 Title: The three-dimensional solution structure of the NK-2 homeodomain from Drosophila. Authors: Tsao, D.H. / Gruschus, J.M. / Wang, L.H. / Nirenberg, M. / Ferretti, J.A. #1: Journal: Biochemistry / Year: 1994 Title: Elongation of Helix III of the Nk-2 Homeodomain Upon Binding to DNA: A Secondary Structure Study by NMR Authors: Tsao, D.H. / Gruschus, J.M. / Wang, L.H. / Nirenberg, M. / Ferretti, J.A. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1vnd.cif.gz | 874.6 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1vnd.ent.gz | 747 KB | Display | PDB format |
PDBx/mmJSON format | 1vnd.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/vn/1vnd ftp://data.pdbj.org/pub/pdb/validation_reports/vn/1vnd | HTTPS FTP |
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-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein | Mass: 9374.741 Da / Num. of mol.: 1 / Fragment: HOMEODOMAIN Source method: isolated from a genetically manipulated source Source: (gene. exp.) Drosophila melanogaster (fruit fly) / Organ: FRUIT / Production host: Escherichia coli (E. coli) / References: UniProt: P22808 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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-Sample preparation
Sample conditions | pH: 4.4 / Temperature: 285 K |
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Crystal grow | *PLUS Method: other / Details: NMR |
-Processing
Software |
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NMR software | Name: X-PLOR / Developer: BRUNGER / Classification: refinement | ||||||||
NMR ensemble | Conformers submitted total number: 30 |