登録情報 データベース : PDB / ID : 1u34 構造の表示 ダウンロードとリンクタイトル 3D NMR structure of the first extracellular domain of CRFR-2beta, a type B1 G-protein coupled receptor 要素Corticotropin releasing factor receptor 2 詳細 キーワード SIGNALING PROTEIN / Beta sheets and Loops機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
gastric motility / negative regulation of defecation / Class B/2 (Secretin family receptors) / skeletal muscle tissue growth / corticotrophin-releasing factor receptor activity / corticotropin-releasing hormone receptor activity / negative regulation of follicle-stimulating hormone secretion / negative regulation of norepinephrine secretion / positive regulation of serotonin secretion / negative regulation of luteinizing hormone secretion ... gastric motility / negative regulation of defecation / Class B/2 (Secretin family receptors) / skeletal muscle tissue growth / corticotrophin-releasing factor receptor activity / corticotropin-releasing hormone receptor activity / negative regulation of follicle-stimulating hormone secretion / negative regulation of norepinephrine secretion / positive regulation of serotonin secretion / negative regulation of luteinizing hormone secretion / G alpha (s) signalling events / negative regulation of epinephrine secretion / catecholamine biosynthetic process / varicosity / negative regulation of calcium ion import / cell body fiber / positive regulation of cAMP-mediated signaling / positive regulation of stress-activated MAPK cascade / positive regulation of blood pressure / : / G protein-coupled peptide receptor activity / negative regulation of insulin secretion involved in cellular response to glucose stimulus / positive regulation of DNA biosynthetic process / positive regulation of heart rate / negative regulation of feeding behavior / peptide hormone binding / axon terminus / epithelial cell differentiation / negative regulation of angiogenesis / regulation of ERK1 and ERK2 cascade / long-term synaptic potentiation / actin filament organization / adenylate cyclase-modulating G protein-coupled receptor signaling pathway / hormone activity / positive regulation of interleukin-6 production / perikaryon / cell surface receptor signaling pathway / G protein-coupled receptor signaling pathway / axon / negative regulation of gene expression / neuronal cell body / dendrite / positive regulation of gene expression / plasma membrane 類似検索 - 分子機能 GPCR, family 2, corticotropin releasing factor receptor, type 2 / GPCR, family 2, corticotropin releasing factor receptor / GPCR, family 2, extracellular hormone receptor domain / Hormone receptor fold / G-protein coupled receptors family 2 signature 1. / Hormone receptor domain / GPCR, family 2, extracellular hormone receptor domain / G-protein coupled receptors family 2 profile 1. / Domain present in hormone receptors / GPCR family 2, extracellular hormone receptor domain superfamily ... GPCR, family 2, corticotropin releasing factor receptor, type 2 / GPCR, family 2, corticotropin releasing factor receptor / GPCR, family 2, extracellular hormone receptor domain / Hormone receptor fold / G-protein coupled receptors family 2 signature 1. / Hormone receptor domain / GPCR, family 2, extracellular hormone receptor domain / G-protein coupled receptors family 2 profile 1. / Domain present in hormone receptors / GPCR family 2, extracellular hormone receptor domain superfamily / G-protein coupled receptors family 2 signature 2. / GPCR, family 2, secretin-like, conserved site / GPCR, family 2, secretin-like / 7 transmembrane receptor (Secretin family) / GPCR, family 2-like / G-protein coupled receptors family 2 profile 2. / Few Secondary Structures / Irregular 類似検索 - ドメイン・相同性生物種 Mus musculus (ハツカネズミ)手法 溶液NMR / distance geometry , simulated annealing , molecular dynamics , torsion angle dynamics 詳細データ登録者 Grace, C.R. / Perrin, M.H. / DiGruccio, M.R. / Miller, C.L. / Rivier, J.E. / Vale, W.W. / Riek, R. 引用ジャーナル : Proc.Natl.Acad.Sci.USA / 年 : 2004タイトル : NMR structure and peptide hormone binding site of the first extracellular domain of a type B1 G protein-coupled receptor著者 : Grace, C.R. / Perrin, M.H. / DiGruccio, M.R. / Miller, C.L. / Rivier, J.E. / Vale, W.W. / Riek, R. 履歴 登録 2004年7月20日 登録サイト : RCSB / 処理サイト : PDBJ改定 1.0 2004年9月7日 Provider : repository / タイプ : Initial release改定 1.1 2008年4月30日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance改定 1.3 2022年3月2日 Group : Database references / Derived calculationsカテゴリ : database_2 / pdbx_struct_assembly ... database_2 / pdbx_struct_assembly / pdbx_struct_oper_list / struct_ref_seq_dif Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details
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