+Open data
-Basic information
Entry | Database: PDB / ID: 1tam | ||||||
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Title | HUMAN IMMUNODEFICIENCY VIRUS, NMR, MINIMIZED AVERAGE STRUCTURE | ||||||
Components | HIV-1 MATRIX PROTEIN | ||||||
Keywords | MATRIX PROTEIN / AIDS / CORE PROTEIN / POLYPROTEIN / MYRISTYLATION / PHOSPHORYLATION | ||||||
Function / homology | Function and homology information integrase activity / Integration of viral DNA into host genomic DNA / Autointegration results in viral DNA circles / Minus-strand DNA synthesis / Plus-strand DNA synthesis / 2-LTR circle formation / Uncoating of the HIV Virion / Vpr-mediated nuclear import of PICs / Early Phase of HIV Life Cycle / Integration of provirus ...integrase activity / Integration of viral DNA into host genomic DNA / Autointegration results in viral DNA circles / Minus-strand DNA synthesis / Plus-strand DNA synthesis / 2-LTR circle formation / Uncoating of the HIV Virion / Vpr-mediated nuclear import of PICs / Early Phase of HIV Life Cycle / Integration of provirus / APOBEC3G mediated resistance to HIV-1 infection / Binding and entry of HIV virion / viral life cycle / Assembly Of The HIV Virion / HIV-1 retropepsin / retroviral ribonuclease H / exoribonuclease H / Budding and maturation of HIV virion / exoribonuclease H activity / protein processing / host multivesicular body / viral genome integration into host DNA / RNA-directed DNA polymerase / establishment of integrated proviral latency / viral penetration into host nucleus / RNA stem-loop binding / RNA-directed DNA polymerase activity / host cell / RNA-DNA hybrid ribonuclease activity / Transferases; Transferring phosphorus-containing groups; Nucleotidyltransferases / peptidase activity / symbiont-mediated suppression of host gene expression / viral nucleocapsid / DNA recombination / DNA-directed DNA polymerase / Hydrolases; Acting on ester bonds / aspartic-type endopeptidase activity / DNA-directed DNA polymerase activity / symbiont entry into host cell / lipid binding / host cell nucleus / host cell plasma membrane / structural molecule activity / virion membrane / DNA binding / zinc ion binding / identical protein binding / membrane Similarity search - Function | ||||||
Biological species | HIV-1 M:B_HXB2R (virus) | ||||||
Method | SOLUTION NMR | ||||||
Authors | Matthews, S. / Barlow, P. / Clark, N. / Kingsman, S. / Kingsman, A. / Campbell, I. | ||||||
Citation | Journal: Biochem.Soc.Trans. / Year: 1995 Title: Refined solution structure of p17, the HIV matrix protein. Authors: Matthews, S. / Barlow, P. / Clark, N. / Kingsman, S. / Kingsman, A. / Campbell, I. #1: Journal: Nature / Year: 1994 Title: Structural Similarity between the P17 Matrix Protein of HIV-1 and Interferon-Gamma Authors: Matthews, S. / Barlow, P. / Boyd, J. / Barton, G. / Russell, R. / Mills, H. / Cunningham, M. / Meyers, N. / Burns, N. / Clark, N. / al., et | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1tam.cif.gz | 53.4 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1tam.ent.gz | 39.3 KB | Display | PDB format |
PDBx/mmJSON format | 1tam.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 1tam_validation.pdf.gz | 244.2 KB | Display | wwPDB validaton report |
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Full document | 1tam_full_validation.pdf.gz | 244 KB | Display | |
Data in XML | 1tam_validation.xml.gz | 4.4 KB | Display | |
Data in CIF | 1tam_validation.cif.gz | 5.6 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/ta/1tam ftp://data.pdbj.org/pub/pdb/validation_reports/ta/1tam | HTTPS FTP |
-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein | Mass: 14907.896 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) HIV-1 M:B_HXB2R (virus) / Genus: Lentivirus / Species: Human immunodeficiency virus 1 / Production host: Escherichia coli (E. coli) / References: UniProt: P04585 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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-Sample preparation
Crystal grow | *PLUS Method: other / Details: NMR |
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-Processing
Software |
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NMR software | Name: X-PLOR / Developer: BRUNGER / Classification: refinement | ||||||||
NMR ensemble | Conformers submitted total number: 1 |