登録情報 | データベース: PDB / ID: 1sbx |
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タイトル | Crystal structure of the Dachshund-homology domain of human SKI |
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要素 | Ski oncogene |
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キーワード | ONCOPROTEIN / winged helix / forkhead |
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機能・相同性 | 機能・相同性情報
nose morphogenesis / histone deacetylase inhibitor activity / myotube differentiation / lens morphogenesis in camera-type eye / negative regulation of Schwann cell proliferation / negative regulation of SMAD protein signal transduction / camera-type eye morphogenesis / olfactory bulb development / myelination in peripheral nervous system / Signaling by BMP ...nose morphogenesis / histone deacetylase inhibitor activity / myotube differentiation / lens morphogenesis in camera-type eye / negative regulation of Schwann cell proliferation / negative regulation of SMAD protein signal transduction / camera-type eye morphogenesis / olfactory bulb development / myelination in peripheral nervous system / Signaling by BMP / negative regulation of activin receptor signaling pathway / camera-type eye development / bone morphogenesis / face morphogenesis / embryonic limb morphogenesis / anterior/posterior axis specification / negative regulation of BMP signaling pathway / cardiac muscle cell proliferation / negative regulation of osteoblast differentiation / positive regulation of DNA binding / roof of mouth development / SMAD binding / somatic stem cell population maintenance / positive regulation of Wnt signaling pathway / skeletal muscle fiber development / negative regulation of fibroblast proliferation / transcription repressor complex / transforming growth factor beta receptor signaling pathway / negative regulation of transforming growth factor beta receptor signaling pathway / neural tube closure / cell motility / Downregulation of SMAD2/3:SMAD4 transcriptional activity / DNA-binding transcription repressor activity, RNA polymerase II-specific / PML body / retina development in camera-type eye / DNA-binding transcription factor binding / transcription regulator complex / DNA-binding transcription factor activity, RNA polymerase II-specific / nuclear body / RNA polymerase II cis-regulatory region sequence-specific DNA binding / protein domain specific binding / negative regulation of cell population proliferation / centrosome / ubiquitin protein ligase binding / protein kinase binding / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / protein-containing complex / zinc ion binding / nucleoplasm / identical protein binding / nucleus / cytoplasm類似検索 - 分子機能 Ski / : / c-SKI SMAD4-binding domain / Transcription regulator SKI/SnoN / c-SKI Smad4 binding domain / c-SKI Smad4 binding domain / SKI/SNO/DAC domain / Ski-like, DNA-binding domain superfamily / SKI/SNO/DAC family / Mlu1-box Binding Protein; DNA-binding Domain ...Ski / : / c-SKI SMAD4-binding domain / Transcription regulator SKI/SnoN / c-SKI Smad4 binding domain / c-SKI Smad4 binding domain / SKI/SNO/DAC domain / Ski-like, DNA-binding domain superfamily / SKI/SNO/DAC family / Mlu1-box Binding Protein; DNA-binding Domain / SAND-like domain superfamily / Putative DNA-binding domain superfamily / Roll / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 多波長異常分散 / 解像度: 1.65 Å |
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データ登録者 | Wilson, J.J. / Malakhova, M. / Zhang, R. / Joachimiak, A. / Hegde, R.S. |
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引用 | ジャーナル: Structure / 年: 2004 タイトル: Crystal Structure of the Dachshund Homology Domain of human SKI 著者: Wilson, J.J. / Malakhova, M. / Zhang, R. / Joachimiak, A. / Hegde, R.S. |
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履歴 | 登録 | 2004年2月11日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2004年5月25日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年4月29日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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