- PDB-1okc: structure of mitochondrial ADP/ATP carrier in complex with carbox... -
+
Open data
ID or keywords:
Loading...
-
Basic information
Entry
Database: PDB / ID: 1okc
Title
structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside
Components
ADP, ATP CARRIER PROTEIN HEART ISOFORM T1
Keywords
TRANSPORT PROTEIN / MITOCHONDRIAL TRANSPORTER / NUCLEOTIDE TRANSLOCATION / MEMBRANE PROTEIN / CARRIER PROTEIN
Function / homology
Function and homology information
ATP:ADP antiporter activity / ADP transport / mitochondrial ADP transmembrane transport / oxidative phosphorylation uncoupler activity / Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane / mitochondrial ATP transmembrane transport / adaptive thermogenesis / Mitochondrial protein import / positive regulation of mitophagy / mitochondrial permeability transition pore complex ...ATP:ADP antiporter activity / ADP transport / mitochondrial ADP transmembrane transport / oxidative phosphorylation uncoupler activity / Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane / mitochondrial ATP transmembrane transport / adaptive thermogenesis / Mitochondrial protein import / positive regulation of mitophagy / mitochondrial permeability transition pore complex / negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway / regulation of mitochondrial membrane permeability / mitochondrial membrane / mitochondrial inner membrane Similarity search - Function
HELIX THE OVERALL STRUCTURE CONSISTS OF SIX TRANSMEMBRANE HELICES, MADE UP BY RESIDUES 3-38, 72- ... HELIX THE OVERALL STRUCTURE CONSISTS OF SIX TRANSMEMBRANE HELICES, MADE UP BY RESIDUES 3-38, 72-100, 107-143, 175-200, 208-239 AND 272-291. THERE ARE THREE HELICES ON THE MATRIX SIDE MADE UP BY RESIDUES 52-65, 155-168 AND 252-265.
Mass: 18.015 Da / Num. of mol.: 83 / Source method: isolated from a natural source / Formula: H2O
-
Details
Compound details
CATALYZES THE EXCHANGE OF ADP AND ATP ACROSS THE MITOCHONDRIAL INNER MEMBRANE. MEMBER OF THE ...CATALYZES THE EXCHANGE OF ADP AND ATP ACROSS THE MITOCHONDRIAL INNER MEMBRANE. MEMBER OF THE MITOCHONDRIAL CARRIER FAMILY.
-
Experimental details
-
Experiment
Experiment
Method: X-RAY DIFFRACTION / Number of used crystals: 1
-
Sample preparation
Crystal
Density Matthews: 2.71 Å3/Da / Density % sol: 54.56 % Description: HEAVY ATOM DERIVATIVE DATA SETS WERE COLLECTED ON BEAMLINE BM30A AT ESRF
Crystal grow
pH: 8.5 Details: 30% JEFFAMINE600, 5MM NA CITRATE, 100MM TRIS PH 8.5
In the structure databanks used in Yorodumi, some data are registered as the other names, "COVID-19 virus" and "2019-nCoV". Here are the details of the virus and the list of structure data.
Jan 31, 2019. EMDB accession codes are about to change! (news from PDBe EMDB page)
EMDB accession codes are about to change! (news from PDBe EMDB page)
The allocation of 4 digits for EMDB accession codes will soon come to an end. Whilst these codes will remain in use, new EMDB accession codes will include an additional digit and will expand incrementally as the available range of codes is exhausted. The current 4-digit format prefixed with “EMD-” (i.e. EMD-XXXX) will advance to a 5-digit format (i.e. EMD-XXXXX), and so on. It is currently estimated that the 4-digit codes will be depleted around Spring 2019, at which point the 5-digit format will come into force.
The EM Navigator/Yorodumi systems omit the EMD- prefix.
Related info.:Q: What is EMD? / ID/Accession-code notation in Yorodumi/EM Navigator
Yorodumi is a browser for structure data from EMDB, PDB, SASBDB, etc.
This page is also the successor to EM Navigator detail page, and also detail information page/front-end page for Omokage search.
The word "yorodu" (or yorozu) is an old Japanese word meaning "ten thousand". "mi" (miru) is to see.
Related info.:EMDB / PDB / SASBDB / Comparison of 3 databanks / Yorodumi Search / Aug 31, 2016. New EM Navigator & Yorodumi / Yorodumi Papers / Jmol/JSmol / Function and homology information / Changes in new EM Navigator and Yorodumi