登録情報 | データベース: PDB / ID: 1n8p |
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タイトル | Crystal Structure of cystathionine gamma-lyase from yeast |
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要素 | Cystathionine gamma-lyase |
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キーワード | LYASE / three open alpha/beta structures |
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機能・相同性 | 機能・相同性情報
Degradation of cysteine and homocysteine / Cysteine formation from homocysteine / positive regulation of hydrogen sulfide biosynthetic process / cysteine-S-conjugate beta-lyase activity / carbon-sulfur lyase activity / cystathionine gamma-lyase / L-cystine L-cysteine-lyase (deaminating) / cystathionine gamma-lyase activity / cysteine biosynthetic process via cystathionine / L-cysteine desulfhydrase activity ...Degradation of cysteine and homocysteine / Cysteine formation from homocysteine / positive regulation of hydrogen sulfide biosynthetic process / cysteine-S-conjugate beta-lyase activity / carbon-sulfur lyase activity / cystathionine gamma-lyase / L-cystine L-cysteine-lyase (deaminating) / cystathionine gamma-lyase activity / cysteine biosynthetic process via cystathionine / L-cysteine desulfhydrase activity / cysteine biosynthetic process / transsulfuration / pyridoxal phosphate binding / nucleus / cytoplasm類似検索 - 分子機能 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. / Cys/Met metabolism, pyridoxal phosphate-dependent enzyme / Cys/Met metabolism PLP-dependent enzyme / Aspartate Aminotransferase, domain 1 / Aspartate Aminotransferase, domain 1 / Aspartate Aminotransferase; domain 2 / Type I PLP-dependent aspartate aminotransferase-like (Major domain) / Pyridoxal phosphate-dependent transferase, small domain / Pyridoxal phosphate-dependent transferase, major domain / Pyridoxal phosphate-dependent transferase ...Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. / Cys/Met metabolism, pyridoxal phosphate-dependent enzyme / Cys/Met metabolism PLP-dependent enzyme / Aspartate Aminotransferase, domain 1 / Aspartate Aminotransferase, domain 1 / Aspartate Aminotransferase; domain 2 / Type I PLP-dependent aspartate aminotransferase-like (Major domain) / Pyridoxal phosphate-dependent transferase, small domain / Pyridoxal phosphate-dependent transferase, major domain / Pyridoxal phosphate-dependent transferase / Alpha-Beta Complex / 3-Layer(aba) Sandwich / Alpha Beta類似検索 - ドメイン・相同性 PYRIDOXAL-5'-PHOSPHATE / Cystathionine gamma-lyase類似検索 - 構成要素 |
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生物種 | ![](img/tx_yeast.gif) Saccharomyces cerevisiae (パン酵母) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.6 Å |
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データ登録者 | Messerschmidt, A. / Worbs, M. / Steegborn, C. / Wahl, M.C. / Huber, R. / Clausen, T. |
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引用 | ジャーナル: BIOL.CHEM. / 年: 2003 タイトル: Determinants of Enzymatic Specificity in the Cys-Met-Metabolism PLP-Dependent Enzymes Family: Crystal Structure of Cystathionine gamma-lyase from Yeast and Intrafamiliar Structural Comparison 著者: Messerschmidt, A. / Worbs, M. / Steegborn, C. / Wahl, M.C. / Huber, R. / Laber, B. / Clausen, T. |
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履歴 | 登録 | 2002年11月21日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2002年12月4日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年4月28日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Non-polymer description / Version format compliance |
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改定 1.3 | 2023年8月16日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_conn / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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