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Open data
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Basic information
Entry | Database: PDB / ID: 1mq1 | ||||||
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Title | Ca2+-S100B-TRTK-12 complex | ||||||
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![]() | METAL BINDING PROTEIN / protein-peptide complex / EF-hand | ||||||
Function / homology | ![]() WASH complex / F-actin capping protein complex / adaptive thermogenesis / sympathetic neuron projection extension / RAGE receptor binding / cell junction assembly / COPI-independent Golgi-to-ER retrograde traffic / ion binding / barbed-end actin filament capping / S100 protein binding ...WASH complex / F-actin capping protein complex / adaptive thermogenesis / sympathetic neuron projection extension / RAGE receptor binding / cell junction assembly / COPI-independent Golgi-to-ER retrograde traffic / ion binding / barbed-end actin filament capping / S100 protein binding / Sensory processing of sound by inner hair cells of the cochlea / regulation of neuronal synaptic plasticity / TRAF6 mediated NF-kB activation / Advanced glycosylation endproduct receptor signaling / COPI-mediated anterograde transport / Nuclear signaling by ERBB4 / ruffle / HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand / MHC class II antigen presentation / positive regulation of neuron differentiation / Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation / axonogenesis / sarcoplasmic reticulum / central nervous system development / TAK1-dependent IKK and NF-kappa-B activation / tau protein binding / memory / calcium-dependent protein binding / actin filament binding / actin cytoskeleton / actin binding / Factors involved in megakaryocyte development and platelet production / actin cytoskeleton organization / protein-containing complex assembly / positive regulation of canonical NF-kappaB signal transduction / learning or memory / cytoskeleton / cell adhesion / cadherin binding / intracellular membrane-bounded organelle / neuronal cell body / calcium ion binding / positive regulation of cell population proliferation / perinuclear region of cytoplasm / protein homodimerization activity / extracellular space / zinc ion binding / extracellular exosome / extracellular region / nucleoplasm / identical protein binding / nucleus / cytoplasm / cytosol Similarity search - Function | ||||||
Biological species | ![]() | ||||||
Method | SOLUTION NMR | ||||||
![]() | McClintock, K.A. / Shaw, G.S. | ||||||
![]() | ![]() Title: A novel S100 target conformation is revealed by the solution structure of the Ca2+-S100B-TRTK-12 complex. Authors: McClintock, K.A. / Shaw, G.S. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 1.1 MB | Display | ![]() |
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PDB format | ![]() | 913.7 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 376.9 KB | Display | ![]() |
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Full document | ![]() | 841.2 KB | Display | |
Data in XML | ![]() | 83.5 KB | Display | |
Data in CIF | ![]() | 121.7 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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NMR ensembles |
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Components
#1: Protein | Mass: 10595.841 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() #2: Protein/peptide | Mass: 1477.728 Da / Num. of mol.: 2 / Fragment: TRTK-12 peptide, RESIDUES 265-276 / Source method: obtained synthetically / Details: The peptide is chemically synthesized. / References: UniProt: P52907 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||||||||||
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NMR experiment |
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Sample preparation
Details |
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Sample conditions | Ionic strength: 35 mM KCl / pH: 7.05 / Pressure: ambient / Temperature: 308 K | |||||||||||||||
Crystal grow | *PLUS Method: other / Details: NMR |
-NMR measurement
Radiation | Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M | |||||||||||||||
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Radiation wavelength | Relative weight: 1 | |||||||||||||||
NMR spectrometer |
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Processing
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NMR representative | Selection criteria: closest to the average | ||||||||||||||||||||||||
NMR ensemble | Conformer selection criteria: structures with the lowest energy Conformers calculated total number: 80 / Conformers submitted total number: 17 |